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An Accurate and Comprehensive Clinical Sequencing Assay for Cancer Targeted and Immunotherapies |
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| Authors: | Jingyu Cao Lijuan Chen Heng Li Hui Chen Jicheng Yao Shuo Mu Wenjin Liu Peng Zhang Yuwei Cheng Binbin Liu Zhongxiang Hu Donglin Chen Hui Kang Jinwei Hu Aodi Wang Weifeng Wang Ming Yao Gungwei Chrin Xiaoting Wang Wei Zhao Lei Li Luping Xu Weixin Guo Jun Jia Jianhua Chen Kai Wang Gaofeng Li Weiwei Shi |
| Institution: | 1. Department of Hepatobiliary Surgery, The Affiliated Hospital of Qingdao University, Qingdao, People's Republic of China
Contributed equally.;2. OrigiMed, Shanghai, People's Republic of China Contributed equally.;3. Department of Thoracic Surgery, The Third Affiliated Hospital of Kunming Medical University, Yunnan Tumor Hospital, Kunming, People's Republic of China Contributed equally.;4. OrigiMed, Shanghai, People's Republic of China;5. Program of Computational Biology and Bioinformatics, Yale University, New Haven, Connecticut, USA;6. Department of Medicine, The First Affiliated Hospital, Zhejiang University, Hangzhou, People's Republic of China;7. Department of Hepatobiliary Surgery, The Affiliated Hospital of Qingdao University, Qingdao, People's Republic of China;8. Department of Hepatobiliary Surgery, Shandong Tumor Hospital, Jinan, People's Republic of China;9. Department of General Surgery, The First Affiliated Hospital, Jiaxing College of Medicine, Jiangxi, People's Republic of China;10. Department of Chemotherapy, Meizhou People's Hospital, Meizhou, People's Republic of China;11. Department of Oncology, Dongguan People's Hospital, Dongguan, People's Republic of China;12. Department of Medical Oncology-Chest, Hunan Cancer Hospital, Changsha, People's Republic of China;13. OrigiMed, Shanghai, People's Republic of China Zhejiang University International Hospital, Hangzhou, People's Republic of China;14. Department of Thoracic Surgery, The Third Affiliated Hospital of Kunming Medical University, Yunnan Tumor Hospital, Kunming, People's Republic of China |
| Abstract: | |
| Keywords: | Next-generation sequencing-based assay Targeted therapies and immunotherapies Long insertion and deletion Gene rearrangement Tumor mutational burden Microsatellite instability |