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Degree of MDM2 Amplification Affects Clinical Outcomes in Dedifferentiated Liposarcoma
Authors:Kate Lynn J. Bill  Nathan D. Seligson  John L. Hays  Achal Awasthi  Bryce Demoret  Colin W. Stets  Megan C. Duggan  Manojkumar Bupathi  Guy N. Brock  Sherri Z. Millis  Reena Shakya  Cynthia D. Timmers  Paul E. Wakely Jr.  Raphael E. Pollock  James L. Chen
Affiliation:1. Division of Surgical Oncology, Department of Surgery, The Ohio State University, Columbus, Ohio, USA

Wexner Medical Center and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA

Contributed equally.;2. Wexner Medical Center and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA

Contributed equally.;3. Division of Medical Oncology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The Ohio State University, Columbus, Ohio, USA;4. Division of Medical Oncology, Department of Internal Medicine, The Ohio State University, Columbus, Ohio, USA;5. Department of Biomedical Informatics, The Ohio State University, Columbus, Ohio, USA;6. Wexner Medical Center and Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, USA;7. Foundation Medicine Inc., Cambridge, Massachusetts, USA;8. Department of Pathology, The Ohio State University, Columbus, Ohio, USA;9. Division of Surgical Oncology, Department of Surgery, The Ohio State University, Columbus, Ohio, USA

Abstract:
Keywords:Dedifferentiated liposarcomas  MDM2  Doxorubicin  p53  Biomarker
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