国人英文语言活动区功能磁共振研究

目的利用BOLD功能磁共振，初步探索母语为中文者，说第二语言(L2)英文时大脑的语言相关功能区。方法对22名“晚双语”正常中国人，说英文句子状态下进行BOLD磁共振脑功能成像，探索其L2大脑活动皮层相关功能区。结果说英文时激活的脑区包括：左右侧运动区、左额下回、右额下回、左侧颞上回、岛叶及左右侧小脑。结论BOLD功能磁共振可显示第二语言英文大脑活动相关皮层，是无创性研究人类语言的有力武器。

A fMRI Study of English Cerebral Representation in Chinese-English Bilinguals

Objective To investigate the brain areas asso ciated with Chinese-English bilinguals when they speak English(L2). Methods In order to determine the neural anatomic substra tes employed in repeatedly speaking English,22 Chinese healthy volunteers were p erformed in this study by using blood oxygenation level dependent (BOLD) contras t functional magnetic resonance imaging (fMRI) on a 1.5T system. Results Our block-design fMRI studies had found many cor tic areas that were associated with Chinese-English bilinguals.Those cortic are as were:left motor cortex,left posterior inferior frontal gyrus,left superior te mporal gyrus,left anterior insula and bilateral cerebellum. Conclusion BOLD fMRI can reveal cortic areas that are ass ociated with Chinese-English bilinguals when they speak English (L2),and it mig ht be a powerful utility to engage language research without trauma.