| 替罗非班在急性心肌梗死介入治疗中的疗效 |
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| 引用本文： | 熊婕雯,季波.替罗非班在急性心肌梗死介入治疗中的疗效[J].药物流行病学杂志,2008,17(6). |
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| 作者姓名： | 熊婕雯 季波 |
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| 作者单位： | 广州军区广州总医院药剂科,广州,510010 |
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| 摘 要： | 目的:研究ST段抬高型急性心肌梗死(AMI)患者在急诊行经皮冠状动脉介入术(PCI)中应用替罗非班的有效性和安全性. 方法:患者80名,随机分为试验组(替罗非班+PCI组)40例,对照组(PCI组)40例.观察PCI术前、术后梗死相关动脉(IRA)TIMI血流情况以及患者7d内两组患者心血管事件(MACE)的发生率,及术后两组惠者的出血发生率. 结果:介入术后造影显示替罗非班组患者恢复TIMI 3级血流比例明显高于对照组.住院期间替罗非班组心血管事件发生率较对照组低(P<0.05).而两组间术后出血比例差异无统计学意义. 结论:ST段抬高型急性心肌梗死(AMI)患者在急诊冠状动脉介入术中使用血小板膜糖蛋白Ⅱb/Ⅲa受体拮抗剂替罗非班是有效并且安全的,其疗效优于常规治疗组.
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| 关 键 词： | 替罗非班 心肌梗死 急性 介入治疗 |
Effect of Tirofiban on Patients with Acute Myocardial Infarction During PCI |
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| Xiong Jiewen,Ji Bo.Effect of Tirofiban on Patients with Acute Myocardial Infarction During PCI[J].Chinese Journal of Pharmacoepidemiology,2008,17(6). |
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| Authors: | Xiong Jiewen Ji Bo |
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| Institution: | Xiong Jiewen,Ji Bo Department of Pharmacy,Guangzhou Military General Hospital,Guangzhou 510010,China |
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| Abstract: | Objective:To investigate the efficacy and safety of tirofiban on patients with acute myocardial infarction (AMI)during emergency PCI.Method:80 patients with PCI were randomized into a study group(tirofiban+PCI group,n=40)and a controlled group(PCI group n=40).Their angiographic characteristics before and after PCI were collected and studied.The in-hospital cardiovascular events and the bleeding complications were assessed.Result:The patients in the study group were recovered with a higher rate of TIMI 3 gra... |
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| Keywords: | Tirofiban Acute myocardial Infarction Percutaneous coronary intervention |
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