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苦参碱、氧化苦参碱与蛇床子提取物联合抗菌作用研究
引用本文:郭晓蕾,朱思潮,张晨,王怀豫,宝丽. 苦参碱、氧化苦参碱与蛇床子提取物联合抗菌作用研究[J]. 中华中医药学刊, 2011, 0(6): 1398-1400
作者姓名:郭晓蕾  朱思潮  张晨  王怀豫  宝丽
作者单位:无限极(中国)有限公司;中国科学院微生物研究所真菌地衣系统学实验室;
摘    要:目的:探讨苦参碱、氧化苦参碱和蛇床子提取物单独以及联合使用时对大肠杆菌、金黄色葡萄球菌和白色念球菌的抑制作用。方法:以苦参碱、氧化苦参碱和蛇床子提取物为研究对象,通过纸片扩散法测试其单独使用及联合使用时对上述菌种的抑菌圈直径。结果:苦参碱、氧化苦参碱单独使用时对大肠杆菌、金黄色葡萄球菌和白色念球菌均没有抑菌效果,蛇床子提取物对金黄色葡萄球菌有微弱的抑制作用,而苦参碱、氧化苦参碱与蛇床子提取物联用对金黄色葡萄球菌和白色念球菌均有很好的抑制作用。结论:本实验中苦参碱和氧化苦参碱与蛇床子提取物联合使用对测试菌种产生增效作用。

关 键 词:蛇床子提取物  苦参碱  氧化苦参碱  联合抗菌

Study on Combined Antibacterial Activities of Matrine,Oxymatrine and Cnidium Monnieri(L.) Cusson
GUO Xiao-lei,ZHU Si-chao,ZHANG Chen,WANG Huai-yu,BAO Li Company Ltd,/F West Tower PCI Business Building Jianzhong Road,Guangzhou ,Guangdong,China. Study on Combined Antibacterial Activities of Matrine,Oxymatrine and Cnidium Monnieri(L.) Cusson[J]. Chinese Archives of Traditional Chinese Medicine, 2011, 0(6): 1398-1400
Authors:GUO Xiao-lei  ZHU Si-chao  ZHANG Chen  WANG Huai-yu  BAO Li Company Ltd  /F West Tower PCI Business Building Jianzhong Road  Guangzhou   Guangdong  China
Affiliation:GUO Xiao-lei1,ZHU Si-chao2,ZHANG Chen1,WANG Huai-yu1,BAO Li2(1.Infinitus(china) Company Ltd,4/F West Tower PCI Business Building 66 Jianzhong Road,Guangzhou 510665,Guangdong,China,2.Key Lab of Systematic Mycology and Lichenology,Institute of Microbiology,Chinese Academy of Sciences,Beijing 100101,China)
Abstract:Objective:To investigate the interaction of matrine,oxymatrine and Cnidium monnieri(L.) Cusson when used alone and combined with each other against E.coli,Staphylococcus aureus and Candida albicans.Methods: We analyzed the antibacterial activity of matrine,oxymatrine and Cnidium monnieri(L.) Cusson in single and combined forms via paper disk diffusion method against the above microorganisms.Results:The results indicated that matrine and oxymatrine have no inhibiton on E.coli,Staphylococcus aureus and Candid...
Keywords:Cnidium monnieri(L.) Cusson  matrine  oxymatrine  combined antibacterial activities  
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