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终末期肝病模型与原发性肝癌患者中医证候的相关性研究
引用本文:文洁,朱德增.终末期肝病模型与原发性肝癌患者中医证候的相关性研究[J].中华中医药学刊,2011(4):873-877.
作者姓名:文洁  朱德增
作者单位:第二军医大学附属长海医院中医科;
摘    要:目的:探讨终末期肝病模型(MELD)与原发性肝癌患者中医证候的相关性。方法:回顾性分析278例原发性肝癌患者资料。采用判别分析研究MELD评分与患者中医证候的相关性。结果:中医辨证为单证、两证、三证和四证相兼(包括四证以上)患者间的MELD评分差异有统计学意义(F=8.322,P=0.000);MELD评分按照单证、两证、三证和四证相兼的顺序逐渐递增。MELD评分<6分、6~10分和>10分判别患者的中医证候是单证、两证、三证或四证相兼的符合率分别为48.3%、65.1%和94.3%。结论:MELD评分与原发性肝癌患者中医证候具有一定的相关性;患者的MELD评分越高,患者的中医证候越复杂;当MELD评分>10分时,患者多为复合证。

关 键 词:肝肿瘤  中医  证候  终末期肝病模型

Model for End-stage Liver Disease Score and Syndromes of TCM in Patients with Primary Hepatic Cancer
WEN Jie,ZHU De-zeng.Model for End-stage Liver Disease Score and Syndromes of TCM in Patients with Primary Hepatic Cancer[J].Chinese Archives of Traditional Chinese Medicine,2011(4):873-877.
Authors:WEN Jie  ZHU De-zeng
Institution:WEN Jie,ZHU De-zeng(Department of Traditional Chinese Medicine,Changhai Hospital,Second Military Medical University,Shanghai 200433,China)
Abstract:Objective: To investigate the relationship between model for end-stage liver disease(MELD) score and syndromes of TCM in patients with primary hepatic cancer(PHC).Methods: A total of 278 patients with PHC were enrolled into the study from January 2005 to April 2009.MELD score was calculated for each patient following the original formula on the first day of admission.All patients were followed up at least 1 year.Discriminant analysis was used to estimate the correlation and significance between the syndrome...
Keywords:liver neoplasms  TCM  syndrome  MELD  
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