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补肾健脾中药清除乙肝病毒携带者免疫耐受的临床疗效观察
引用本文:翁卫东.补肾健脾中药清除乙肝病毒携带者免疫耐受的临床疗效观察[J].中华中医药学刊,2011(7):1576-1577.
作者姓名:翁卫东
作者单位:浙江省立同德医院感染科;
基金项目:浙江省中医药管理局基金资助项目(2009WA008)
摘    要:目的:观察补肾健脾中药对活动性乙肝病毒携带者肝功能和病毒学指标的影响。方法:将200例HBeAg和HBVDNA双阳性的乙肝病毒携带者随机分为对照组和治疗组,每组100例。治疗组予补肾健脾中药口服24周,对照组不予任何药物治疗,观察两组患者12周和24周时肝功能、HBVDNA、HBeAg的变化。结果:12周时,两组患者肝功能、HBeAg和HBVDNA log平均值下降幅度无显著性差异(P>0.05);24周时,两组患者肝功能和HBVDNA log平均值下降幅度有显著性差异(P<0.05)。结论:用补肾健脾中药对活动性乙肝病毒携带者进行医学干预,可以打破免疫耐受,降低乙肝病毒的复制水平,为进一步抗病毒治疗创造条件,且安全性良好。

关 键 词:中药  乙肝病毒携带者  免疫耐受

Clinical Study of the Traditional Chinese Medicine Decoction in the Treament of Eliminating the hepatitis B virus immune tolerance
WENG Wei-dong.Clinical Study of the Traditional Chinese Medicine Decoction in the Treament of Eliminating the hepatitis B virus immune tolerance[J].Chinese Archives of Traditional Chinese Medicine,2011(7):1576-1577.
Authors:WENG Wei-dong
Institution:WENG Wei-dong(Tongde Hospital of Zhejiang Province,Hangzhou 310012,Zhejiang,China)
Abstract:Objective:To observe the clinical efficacy of traditional Chinese medicine decoction(TCM) in patients with Hepatitis B carriers.Liver function and virology index were detected.Methods:200 cases of HBVDNA double HBeAg positive Hepatitis B carriers were randomly divided into treatment group and control group,each group has 100 cases.The patients in treatment group were treated with TCM for 24 weeks,while the patients in control group were not any medications,The liver function and HBVDNA and HBeAg load were d...
Keywords:traditional Chinese medicine decoction  hepatitis B carriers  immune tolerance  
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