| 低氧及运动致大鼠骨骼肌形态学改变的实验研究 |
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| 引用本文： | 余斌,钟世镇,黄智,王志芳,汪志中,侯振海.低氧及运动致大鼠骨骼肌形态学改变的实验研究[J].中华创伤骨科杂志,2005,7(7):672-675. |
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| 作者姓名： | 余斌 钟世镇 黄智 王志芳 汪志中 侯振海 |
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| 作者单位： | 南方医科大学南方医院创伤骨科
510515广州市(余斌，黄智，王志芳，汪志中)，南方医科大学南方医院临床解剖研究所
510515广州市(钟世镇)，南方医科大学南方医院创伤骨科 510515广州市(侯振海) |
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| 基金项目： | 广东省医学科学技术研究基金(A2002402)，军队“十五”医药卫生科研基金(A类)(01MA136) |
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| 摘 要： | 目的观察低氧及低氧复合运动时,大鼠体重及腓肠肌显微、超微结构的变化,旨在探讨低氧状态下适当运动对骨骼肌的影响。方法建立大鼠低氧及低氧复合运动模型,运用光镜及透射电镜观察大鼠腓肠肌显微、超微结构的变化。结果低氧复合运动组较低氧安静组大鼠体重差异有显著性意义(P<0.05)。低氧复合运动组骨骼肌结构正常,线粒体数量增加,骨骼肌纤维增粗,毛细血管增生。结论低氧复合适当的运动能够维持骨骼肌的正常形态,增强骨骼肌的有氧代谢,起到保护骨骼肌的作用,从而提高骨骼肌的低氧适应能力,促进低氧习服。
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| 关 键 词： | 低氧 运动 骨骼肌 显微结构 超微结构 |
| 文章编号： | 1671-7600(2005)07-0672-04 |
| 修稿时间： | 2004年11月12 |
The experimental research of morphological changes in skeletal muscles of rats under hypoxia combined with training |
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| YU Bin,ZHONG Shi-zhen,HUANG Zhi,WANG Zhi-fang,WANG Zhi-zhong,HOU Zhen-hai.The experimental research of morphological changes in skeletal muscles of rats under hypoxia combined with training[J].Chinese Journal of Orthopaedic Trauma,2005,7(7):672-675. |
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| Authors: | YU Bin ZHONG Shi-zhen HUANG Zhi WANG Zhi-fang WANG Zhi-zhong HOU Zhen-hai |
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| Institution: | YU Bin1,ZHONG Shi-zhen2,HUANG Zhi1,WANG Zhi-fang1,WANG Zhi-zhong1,HOU Zhen-hai11Department Orthopaedic Trauma,Nanfang Hospital,Southern Medical University,Gangzhou 510515,China2Department of Human Anatomy,Southern Medical University,Guangzhou 510515,ChinaSupported by Guangdong Funds for Medical Research |
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| Abstract: | Objective To observe changes in weight, microstructure and ultrastructure of gastrocnemius of rats after hypoxia and hypoxia combined with training, in order to understand the effects of proper training under hypoxia on skeletal muscles. Methods The animal models under hypoxia and hypoxia combined with training were set up and then the changes in microstructure and ultrastructure of the rat gastrocnemius were observed by an electron microscope. Results In the hypoxia training group, the weights differed significantly from those in the hypoxia non-training group (P< 0.05). Also in the hypoxia training group, normal structure of skeletal muscles, hyperplasia of muscle fibers and capillary vessels, an increase of chondriosome could be observed. Conclusion Proper training under hypoxia can maintain normal structure of skeletal muscles and protect them by improving their aerobic-metabolizability and enhancing their accustomization to hypoxia. |
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| Keywords: | Hypoxia Training Skeletal muscle Microstructure Ultrastructure |
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