| 紫堇属植物生物碱的化学——青海高原四种紫堇属植物生物碱的化学研究 |
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| 引用本文： | 方起程,林茂,翁庆梅,朱朝德,刘欣. 紫堇属植物生物碱的化学——青海高原四种紫堇属植物生物碱的化学研究[J]. 药学学报, 1981, 16(10): 798-800 |
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| 作者姓名： | 方起程 林茂 翁庆梅 朱朝德 刘欣 |
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| 作者单位： | 中国医学科学院药物研究所 北京(方起程，林茂，翁庆梅，朱朝德)，中国医学科学院药物研究所 北京(刘欣) |
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| 摘 要： | 中草药夏天无(Corydalis decumbens)和苦地丁(Corydalis bungeana)的总生物碱,经过临床试用,已作为治疗心血管系统疾病的药物。这两药都是紫堇属植物,且主要含异喹啉类生物碱,根据这些资料,拟从这属植物中寻找治疗心血管系统疾病的药物。我们首先选择了直茎紫堇(Corydalis stricta Steph.)、暗绿紫堇(C.melanochlora Maxim.)、条裂紫堇(C.lineariodes Maxim.)、短尖紫堇(C.mucronifera Maxim.)四种植物,利用离子交换树脂
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| 收稿时间： | 1980-10-09 |
ALKALOIDS OF CORYDALIS——STUDIES ON ALKALOIDS OF FOUR SPECIES OF CORYDALIS FROM QINGHAI PLATEAU |
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| Fang Qicheng,Lin Mao,Weng Qingmei,Zhu Chaode and Liu Xin. ALKALOIDS OF CORYDALIS——STUDIES ON ALKALOIDS OF FOUR SPECIES OF CORYDALIS FROM QINGHAI PLATEAU[J]. Acta pharmaceutica Sinica, 1981, 16(10): 798-800 |
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| Authors: | Fang Qicheng Lin Mao Weng Qingmei Zhu Chaode Liu Xin |
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| Abstract: | In order to search drugs for prevention and treatment of cardio-vascular diseases four species of Corydalis (C. stricta Steph, C. melanochlora Maxim, C lineariodes Maxim, C. mucronifera Maxim) from Qinghai plateau were studied. The total alkaloids were extracted with ion exchange resin method. Eleven alkaloids have been isolated by using column chromatography, preparative TLC and preparative HPLC. Among them, 9 alkaloids have been identified as d-hydrastine, acetylcorynoline, corynoline, d-adlumine, d-corlumidine, protopine, d-adlumidine, d-bicuculline and cheilanthifoline. Another two alkaloids are unknown.Their pharmacological tests are in progress. |
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