老年急性缺血性脑卒中患者早期阿斯匹林治疗的临床对照研究

目的：探讨老年急性缺血性脑卒中早期抗血小板治疗效果，以及降低致残率的临床观察，方法：采用随机双盲对照研究，对入院48小时内急性脑卒中患者，经头颅CT扫描除外脑出血，无阿斯匹林禁忌的给予160mg 1/日口服或安慰剂治疗四周，结果：共入选180例，住院期间阿斯匹林组死亡2例，对照组死亡3例，阿斯匹林组治疗期间63％基本恢复，无再发脑卒中及出血，两组治疗结果比较判别显著（P＜0．05）， 结论：阿斯匹林辅佐治疗，不影响其它常规治疗，药源方便，价廉，具有促进恢复，预防复发作用。

Randomized placebo-controlled trial of early aspirin used in 180 patients with acute is-chaemic stroke in the elderly people

Objective To study a reliable assessment of the antipletelet thes-rapeutic effects and its improvement for disability in survivors of acute ischemic stroke in the elderly people. Methods This study was a randomized placebo-controlled trial in hospital, all patients were attacked with ischemic stroke in 48 hours and demonstrated by CT. Treatment of aspirin was 160mg per day and continued 4weeks. Results There were two died cases in aspirin group and three in control group. And it was significantly fewer recurrent ischacmic strokes and hemorrhagic strokes in the aspirin group than in control grous (P < 0. 05). Conclusion This study showed.that aspirin therapy could significantly reduce the mortality and recurrent in the ederly paliants-with ischemic stroke.