(1) Departments of Community Health Sciences and Epidemiology, University of Calgary, 3300 Hospital Drive NW, Calgary, Alberta, T2N 4N1, CANADA
Abstract:
Background
In randomized, controlled trials, antidepressant medications have been shown to reduce the duration of major depressive episodes and to reduce the frequency of relapse during long-term treatment. The epidemiological impact of antidepressant use on episode duration and relapse frequency, however, has not been described.