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Mycobacterium simiae infections: about two cases
Authors:Carrière C  Godreuil S  Gouby A  Vincent V  Marchandin H  Terru D  Delaporte E  Sorokaty J M  Jumas-Bilak E  Van de Perre P
Institution:1. Microbiology Department, Hospital Universitari de Bellvitge, University of Barcelona, IDIBELL, L''Hospitalet de Llobregat, Barcelona, Spain;2. CIBER de Enfermedades Respiratorias, ISCIII, Madrid, Spain;3. Department of Pathology and Experimental Therapeutics, School of Medicine, University of Barcelona, Barcelona, Spain;4. Centro de Investigaciones Biológicas-CSIC, Madrid, Spain;5. CHU de Caen, Service de Microbiologie, Caen, France;6. Université de Caen Normandie, EA4655 U2RM (Équipe ‘Antibio-résistance’), Caen, France;7. CHU de Rennes, Service de Bactériologie-Hygiène hospitalière, Rennes, France;8. CNR de la Résistance aux Antibiotiques (laboratoire associé ‘Entérocoques’), Rennes, France;9. Université de Rennes 1, Unité Inserm U1230, Rennes, France
Abstract:We report two cases of Mycobacterium simiae infections differing by the site of infection, the immunological status of the patients and the diagnostic methods used. The first case is a disseminated infection in an advanced immunosuppressed patient who died quickly confirming the severity of this infection in the context of HIV infection. The second case presented is a respiratory disease in a women with a past history of tuberculosis and an uneventful evolution of the M. simiae infection under treatment. These two cases demontrate the importance of molecular methods to correctly identify M. simiae.
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