| 1-(1-取代苯基)-2-(1H-1,2,4-三唑或苯并三唑基)-O-(取代苄基)乙酮肟醚类化合物的合成及抗真菌活性 |
| |
| 引用本文： | 程潜,李长荣,邢玉芬.1-(1-取代苯基)-2-(1H-1,2,4-三唑或苯并三唑基)-O-(取代苄基)乙酮肟醚类化合物的合成及抗真菌活性[J].药学学报,1997(1). |
| |
| 作者姓名： | 程潜 李长荣 邢玉芬 |
| |
| 作者单位： | 北京农业大学基础科技学院应用化学系 |
| |
| 摘 要： | 报道了２９个新的１（１取代苯基）２（１Ｈ１，２，４三唑或苯并三唑基）Ｏ（取代苄基）乙酮肟醚类化合物的合成与体外抗菌试验。结果表明，大多数化合物对大部分真菌有抑菌活性，化合物Ｔ１，Ｔ４，Ｔ６，Ｔ１１，Ｔ１２，Ｂ１，Ｂ３，Ｂ４和Ｂ６对部分真菌抑菌活性优于或相当于奥昔康唑。
|
| 关 键 词： | 三唑类 苯并三唑类 抗真菌活性 |
SYNTHESIS AND ANTIFUNGAL ACTIVITIES OF 1 (1 SUBSTITUTEDPHENYL) 2 (1H 1,2,4 TRIAZOL OR BENZTRIAZOL 1 YL) O (SUBSTITUTEDBENZYL) ETHANOXIMES |
| |
| Q Cheng,CR Li and YF Xing.SYNTHESIS AND ANTIFUNGAL ACTIVITIES OF 1 (1 SUBSTITUTEDPHENYL) 2 (1H 1,2,4 TRIAZOL OR BENZTRIAZOL 1 YL) O (SUBSTITUTEDBENZYL) ETHANOXIMES[J].Acta Pharmaceutica Sinica,1997(1). |
| |
| Authors: | Q Cheng CR Li and YF Xing |
| |
| Abstract: | Twenty nine 1 (1 substituted phenyl) 2 (1H 1,2,4 triazol or benztriazol 1 yl) O (substituted benzyl) ethanoximes have been synthesized for the first time. Results of preliminary biological test in vitro show that most compounds have antifungal activities against most fungi tested. The antifungal activities of compounds T 1,T 4,T 6,T 11 ,T 12 ,B 1,B 3,B 4 and B 6 are better than or comparable to the activities of the lead compound oxiconazole against some fungi. |
| |
| Keywords: | Triazole Benztriazole Antifungal activity |
| 本文献已被 CNKI 等数据库收录！ |
|
