Autoantibody in a patient with chronic hepatitis C virus infection showing complete remission after interferon therapy |
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Authors: | Akashi Yoshihiro Inoh Masayuki Seto Kunio Gamo Naoyuki Kuboki Makoto Kurata Noriyuki |
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Institution: | Department of Internal Medicine, Kinashi Ohbayashi Hospital, Kagawa, Japan. akashi@niji.or.jp |
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Abstract: | A 42-year-old woman was admitted to Kinashi Ohbayashi Hospital for liver dysfunction. She presented with hepatitis C viral infection accompanied by autoimmune hepatitis-like serological manifestations, such as antinuclear antibody (ANA), antismooth muscle cell antibody and especially anti-ribonucleoprotein (RNP) antibody and anti-SSB antibody. After interferon therapy, hepatitis C virus was not detected and ANA, anti-RNP antibody and anti-SSB antibody disappeared. To our knowledge, this is the first reported hepatitis C patient showing anti-RNP antibody and anti-SSB antibody, having complete remission after interferon therapy. |
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Keywords: | anti-RNP antibody anti-SSB antibody hepatitis C lupus-like syndrome |
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