针药并用治疗轻度认知功能障碍临床观察

目的评价针刺配合安理申治疗轻度认知功能障碍的临床疗效。方法从诊断为轻度认知功能障碍患者中辨证为肝肾阴虚证型的60例患者作为研究对象,随机分为针刺组、针药组、西药组三组,应用简易智力状态检查量表（MMSE）、蒙特利尔认知量表（MoCA）,检查P300的潜伏期和波幅进行评估。结果针药组与针刺组、西药组相比,MMSE和MoCA量表评分,P300的潜伏期和波幅差异均有统计学意义（P〈0.05）;针刺组与西药组相比,MMSE和MoCA量表评分及P300潜伏期和波幅差异无统计学意义（P〉0.05）。结论在三种治疗方法中,针刺配合盐酸多奈哌齐（安理申）治疗肝肾阴虚型轻度认知功能障碍效果最好。

Clinical Observation on the Treatment of Mild Cognitive Impairment by Combined Acupuncture and Medication

Objective To evaluate the therapeutic effect of acupuncture plus medication in the treatment of mild cognitive impairment.Method Sixty subjects diagnosed with mild cognitive impairment of liver-kidney insufficiency type were randomly assigned to an acupuncture group,an acupuncture-medication group and a medication group.The Mini-Mental State Examination（MMSE）,Montreal Cognitive Assessment（MoCA）,as well as the measurement of P300 latency and amplitude were adopted in the evaluation.Results In comparison of MMSE,MoCA,and P300 latency and amplitude,the results in the acupuncture-medication group were significantly different from that in the acupuncture group and medication group（P0.05）;but the differences between the acupuncture group and medication group were not statistically significant（P0.05）.Conclusion Among the three solutions,acupuncture plus medication is the best in the treatment of mild cognitive impairment of liver-kidney insufficiency type.