小儿支原体感染与免疫性血小板减少症的临床观察

目的:探讨小儿支原体感染(MP)与免疫性血小板减少症(ITP)的相关性。方法:检测ITP患儿血MP-IgM,对阳性者分别应用甲泼尼龙(Pred)+丙种球蛋白(IVIG)+红霉素及Pred+IVIG方案治疗。结果:MP-IgM阳性的ITP患儿发病年龄明显大于阴性组,且程度较重(P<0.05),应用Pred+IVIG+红霉素方案治疗患儿,效果明显优于Pred+IVIG方案(P<0.05)。结论:儿童MP感染与ITP密切相关,治疗ITP基础上加用红霉素效果显著。

Clinical observation of mycoplasma infections and immune thrombocytopenia in children

Objective：To investigate correlation between mycoplasma infection （MI） and immune thrombocytopenia （ITP） inchildren. Methods：The amount of MP-IgM in the children with ITP was determined. If MP-IgM （＋）, methylprednisolone （Pred）＋globulin （IVIG）＋Erythromycin was used; if MP-IgM （-）, Pred＋IVIG was used. Results： The MP-IgM （＋） children with ITP weresignificantly older than those with MP-IgM （-）, and had more severe clinical manifestations （P〈0. 05）. The efficacy of Pred＋IVIG＋Erythromycin regimen was better than that of Pred＋IVIG solution （P〈0. 05）. Conclusions： ITP in children is closely related to MPIgMinfection, therefore, Erythromycin should be included in the conventional treatment to strengthen the efficacy.