Foley catheter versus intra-vaginal misoprostol for induction of labor in post-term gestations

Objective

To investigate whether a fluid filled intra-uterine extra-amniotic Foley catheter is an effective alternative to vaginal misoprostol in inducing labor in primigravid women with post-term gestations.

Patients and methods

A prospective quasi-randomized controlled trial was designed and 100 primigravid women with post-term gestations were enrolled and equally allocated into two groups. A fluid filled intra-uterine extra-amniotic Foley catheter was inserted in women of group I. Women in group II received 25 microgram misoprostol vaginally every 4?h. Artificial rupture of membranes was performed for all women when their cervices reached 3?C4?cm dilatation followed by oxytocin infusion if needed. The main primary outcome parameter was the induction to delivery interval. Results were tabulated and statistically analyzed.

Results

No significant difference was noted in any of the demographic data between both groups. The induction to delivery interval was shorter in the Foley group (897.36?±?116.0 vs. 960.98?±?94.18?min; P?=?0.003). There were 34 cases which needed oxytocin augmentation in group I compared to 11 cases in group II (P?Conclusion Fluid filled Foley catheter seems to be superior to 25???g vaginal misoprostol regimen, when used to induce labor in primigravidae with post-term gestations with the advantage of having a shorter induction delivery interval, but more need for oxytocin augmentation.