| STAMP2基因多态性与新疆维吾尔族男性原发性高血压相关性研究 |
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| 引用本文： | 毕云伟,严治涛,李南方,郭艳英,梁登攀,姚晓光,王红梅.STAMP2基因多态性与新疆维吾尔族男性原发性高血压相关性研究[J].临床心血管病杂志,2011,27(7):539-542. |
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| 作者姓名： | 毕云伟 严治涛 李南方 郭艳英 梁登攀 姚晓光 王红梅 |
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| 作者单位： | 1. 新疆医科大学研究生院研究生,乌鲁木齐,830054
2. 新疆维吾尔自治区人民医院高血压科,新疆高血压诊断治疗研究中心 |
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| 基金项目： | 新疆维吾尔自治区重点实验室"新疆高血压病研究实验室"资助 |
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| 摘 要： | 目的:研究STAMP2基因多态性与新疆维吾尔族男性原发性高血压(EH)相关性.方法:采用以流行病学调查为基础的病例-对照研究,选取291例维吾尔族男性EH患者和445例男性正常血压者作为研究对象,首先选取STAMP2基因功能区的变异位点,选取代表性变异位点应用TaqMan-PCR在大样本人群中进行基因型鉴定及病例-对照...
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| 关 键 词： | 高血压 STAMP2 遗传多态性 维吾尔族 男性 |
Genetic polymorphisms of the STAMP2 and essential hypertension in men of Uygur Xinjiang population |
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| BI Yunwei,YAN Zhitao,LI Nanfang,GUO Yanying,LIANG Dengpan,YAO Xiaoguang,WANG Hongmei.Genetic polymorphisms of the STAMP2 and essential hypertension in men of Uygur Xinjiang population[J].Journal of Clinical Cardiology,2011,27(7):539-542. |
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| Authors: | BI Yunwei YAN Zhitao LI Nanfang GUO Yanying LIANG Dengpan YAO Xiaoguang WANG Hongmei |
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| Abstract: | Objective:To investigate the relationship between genetic polymorphisms of STAMP2 and essential hypertension in men of Uygur Xinjiang population.Method:The study registed 291 hypertension patients and 445 normotensive controls.The representative variations were selected by TaqMan-PCR method in 736 Uygur subjects.The association between genetic variations of STAMP2 and hypertensive in men in Uygur was analyzed.Result:In the three representative variations genotyped,rs8122,rs1981529 and rs34741656,the essenti... |
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| Keywords: | STAMP2 |
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