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云南省2005-2008年流感病毒监测结果分析
引用本文:赵群,罗春蕊,宁德明,蒋立,向以斌,周永明,常利涛.云南省2005-2008年流感病毒监测结果分析[J].中国公共卫生,2010,26(4).
作者姓名:赵群  罗春蕊  宁德明  蒋立  向以斌  周永明  常利涛
作者单位:云南省疾病预防控制中心急性传染性防治科,昆明,650022
摘    要:目的监测流感流行趋势,了解云南省流感病毒的活动特点及正常人群流感的抗体水平。方法用鸡胚和犬肾细胞(MDCK)分离病毒,用血凝抑制试验半加敏法鉴定分离的毒株和测定血清抗体。结果2005-2008年,从暴发疫情和哨点医院采集的4 346份疑似流感样病例标本中,分离流感病毒588株,分离率为13.5%,其中H1型197株,H3型155株,B型236株。正常人群对所有流感流行株抗体的总阳性率为36%~100%。结论不同型别的毒株在不同年代、不同季节表现出交替占优势的特征,侵袭的人群以儿童为主。所分离流感优势株的型别与人群流感抗体水平的消长情况一致。

关 键 词:流感病毒  流感抗体  流感监测

Influenza virus monitoring in Yunnan province,2005-2008
Abstract:Objective To find out epidemic characteristics and antibody level of influenza virus among health people in Yunnan province.Methods The chick embryo and MDCK cell were used for separation of virus,and the isolated strain was identified and serum antibody measured through hemagglutination inhibition(HI)test.Results The number of specimen tested was 4 346 and the number of positive specimen was 588 with a positive rate of 13.5%.Among the influenza virus,the H1 type was 197;H3 type was 155 and B type was 236.The total positive rate of all influenza strain antibodies among healthy people was 36%-100%.Conclusion Different types of influenza virus predominate alternatively and are consistent with the rise and fall of influenza antibody level in the population.
Keywords:influenza virus  influenza antibody  influenza surveillance
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