| 急性冠状动脉综合征患者血清单核细胞趋化蛋白-1和干细胞因子的变化 |
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| 引用本文： | 邓争荣,李尚俭,朱宏海,王军奎,官功昌,梁磊,刘新宏,陈新义.急性冠状动脉综合征患者血清单核细胞趋化蛋白-1和干细胞因子的变化[J].临床心血管病杂志,2011,27(7). |
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| 作者姓名： | 邓争荣 李尚俭 朱宏海 王军奎 官功昌 梁磊 刘新宏 陈新义 |
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| 作者单位： | 陕西省人民医院心内科,西安,710068 |
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| 摘 要： | 目的:检测急性冠状动脉综合征(ACS)患者血清单核细胞趋化蛋白-1(MCP-1)和干细胞因子(SCF)的变化,探讨MCP-1和SCF与ACS的关系.方法:纳入急性心肌梗死患者41例,不稳定型心绞痛患者45例,对照组32例,应用ELISA法测定其血清MCP-1和SCF的水平.结果:心肌梗死组和心绞痛组MCP-1水平均明显高于对照组(P<0.01和P<0.05).心肌梗死组及心绞痛组SCF水平略高于对照组,但差异无统计学意义.心肌梗死组MCP-1及SCF水平与血白细胞数、中性粒细胞比率及血脂等水平均无明显相关性.结论:ACS患者尤其是急性心肌梗死患者血MCP-1明显升高,SCF亦有所增加.MCP-1和SCF可能与ACS的发生发展及梗死后的心肌修复有关.
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| 关 键 词： | 急性冠状动脉综合征 急性心肌梗死 单核细胞趋化蛋白-1 干细胞因子 |
Changes of serum levels of MCP-1 and SCF in patients with acute coronary syndromes |
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| DENG Zhengrong,LI Shangjian,ZHO Honghai,WANG Junkui,GOAN Gongchang,LIANG Lei,LIU Xinhong,CHEN Xinyi.Changes of serum levels of MCP-1 and SCF in patients with acute coronary syndromes[J].Journal of Clinical Cardiology,2011,27(7). |
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| Authors: | DENG Zhengrong LI Shangjian ZHO Honghai WANG Junkui GOAN Gongchang LIANG Lei LIU Xinhong CHEN Xinyi |
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| Institution: | DENG Zhengrong LI Shangjian ZHO Honghai WANG Junkui GOAN Gongchang LIANG Lei LIU Xinhong CHEN Xinyi(Department of Cardiology,Shaanxi Provincial People's Hosptial,Xian,710068,China) |
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| Abstract: | Objective:To investigate the changes of serum monocyte chemotactic protein-1(MCP-1) and stem cell factor(SCF) in patients with acute coronary syndrome(ACS) and theirs possible relationship with ACS.Method:41 patients with acute myocardial infarction(AMI),45 patients with unstable angina(UA) and 32 controls were enrolled.The serum levels of MCP-1 and SCF were measured by ELISA in all subjects.Result:The serum levels of MCP-1 in AMI and UA patients were significantly higher than that in controls(P<0.01 and P<... |
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| Keywords: | acute coronary syndrome acute myocardial infarction monocyte chemotactic protein-1 stem cell factor |
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