煤工尘肺的CT定量研究

目的 探讨CT定量对煤工尘肺的诊断价值。方法 对87例不同期别的煤工尘肺患者和正常对照组（17例）分别在主动脉弓顶、隆突、气管分叉下3cm平面进行HRCT扫描，对其图像用CT密度直方图的特定区域－1024－0HU进行测试，计算出具有不同CT值的象素所占的百分数，并统计其特定范围内密度值的比率。结果 正常对照组CT密度值在－983～－778HU范围内为87．31％，I、Ⅱ、Ⅲ期煤工尘肺CT密度值在此范围内分别为80．51、75．27％、72．99％。各组间差异均有显著意义（P＜0．01）。结论 CT定量直方图信息可观测到煤工尘肺纤维化及其程度，结果客观、可靠，具有较高的诊断价值。

CT quanitative study of coal miner' s pneumoconiosis

OBJECTIVE: To study the value of CT quantitativeness in the diagnosis of coal miner's pneumoconiosis. METHODS: 104 cases were examined by HRCT scan at top of aortic arc, carina of trachea, 3 cm below the bifurcation of bronchi, among them there were 87 patients with different stages of coal miner's pneumoconiosis, 17 cases of normal males as the control group. All images were determined by CT density histogram at specific region (- 1,024-0 HU). Calculated the percentage of each pixel included a varying number of CT value, and the ratio of density values in the specific region. RESULTS: The ratio of density values in the region of -983 (-) -778 HU was 87.31% in normal control group, and 80.51%, 75.27% and 72.99% respectively in the I, II, III stages of coal miner's pneumoconiosis. There were statistically significant differences among the groups (P < 0.01). CONCLUSION: CT quantitative histogram information was able to observe the fibrosis and its degree of coal miner's pneumoconiosis. It has a good diagnostic value for its reliability and objectiveness.