氯诺昔康超前镇痛用于甲状腺手术的临床观察

目的:观察氯诺昔康对甲状腺手术的超前镇痛效果。方法:选取择期行甲状腺次全切除的患者50例,麻醉方法均为颈丛神经阻滞,随机分成氯诺昔康组(A组)和对照组(B组),分别于麻醉前30min静脉注射氯诺昔康16mg(A组)或生理盐水4ml(B组)。通过下列指标评价临床效果:VAS评分;芬太尼的用量及给药次数;术中呼吸循环指标;Ramsay评分;术后24h内不良反应如恶心呕吐的发生情况。结果:与B组比较,A组术中VAS评分较低,芬太尼用量及给药次数减少,术后恶心呕吐等不良反应较少(P<0.05)。结论:氯诺昔康对甲状腺手术的超前镇痛效果好,不良反应少。

Clinical Observation about Preemptive Analgesia with lornoxicam for Patients receiving Thyoidectomy

Objective To investigate preemptive analgesic effect of lornoxicam in patients receiving thyoidectomhy.Methods 50 patients receiving thyoidectomy under cervical plexus block were randomized to receive intravenously either lornoxicam 16 mg (group A) or normal saline 4 ml (group B) 30 minutes before cervical plexus block.The clinical responses were evaluated using the VAS Score,volume of fentanyl,Ramsay sedation scale,indexes of respiratory and circulation system,andadverse events within 24 hours postoperation.Results Compared with the normal saline group,patients administrated with lornoxicam showed lower VAS score,and had less volume and frequency of fentanyl.(P<0.05),Patients experienced fewer side-effects such as nausea and vomiting.Conclusion Preemptive analgesia with lornoxicam 16 mg can provide sufficient analgesic effects in the thyoidectomy.