兔胫骨骨缺损原位骨延长实验研究

方法:本实验采用24只新西兰成熟白兔,每组各12只.治疗组,用金属重物由高处垂直坠落致兔胫骨中下段开放粉碎骨折,然后再截除1cm的碎骨,制成骨缺损的模型;对照组, 胫骨中下段用锯截除1cm胫骨,另行胫骨中上段截骨.二组均上外固定支架固定,术后10天,骨折端开始延长,每天延长1mm.结果:二组骨缺损延长1cm,骨折均愈合,二组在X线照片、大体标本外观及病理切片观察均无明显差异.结论:骨缺损能通过原位骨延长治疗取得成功,这对临床治疗骨缺损提供多一种治疗方法.

Rabbit Experiment Research of the Tibial Defect by Primary Bone Lengthening

Methods:Twenty -four skeletally mature New Zealand White rabbits were divided into two e-qual groups : treatment group , with metal heavy thing by highs vertical fall sending on mid and low segment of the tibial shaft formed opening and comminuted fracture , then again section divide out 1 cm smash bone , made bone defect's mode; Confer group, on mid and low segment of the tibial shaft with saw section divide out 1 cm bone, other on mid and high segment of the tibial shaft section bone. Two groups with use of external fixator, lengthening at bone defect site was begun ten days later, every day lengthening 1 mm. Results: Two groups bone defect lengthening 1cm and fracture healing, no significant differences were found between the groups with respect to X -ray photo, specimen and pathology. Conclusions: Primary bone lengthening were effective for the reconstruction of bone defect ,this method provide a new therapeutic option to treat dia-physeal segmental bone defects.