针刺对比西药改善阿尔茨海默病患者认知功能障碍和精神行为症状的临床研究现状与分析＊

阿尔茨海默病（Alzheimer''s disease,AD）是一种起病隐匿且呈进行性发展的神经系统退行性疾病。临床上AD患者主要表现为认知功能障碍（Cognitive Impairment,CI）和精神行为症状（Behavioral and Psychological Symptoms,BPS）,并可能伴有日常功能活动障碍等症状。目前,西药疗法为AD患者的主要治疗方法,但此法只可延缓患者病情,且副作用较多。最新研究认为,针刺疗法对于AD患者CI和BPS等症状具有改善作用。因此,本文对近二十五年针刺对比西药改善AD患者CI和BPS的文献进行梳理,将从针刺方法、针刺选穴、治疗时间以及针刺效果等方面进行分析,发现针刺对轻中度AD患者的CI和BPS治疗效果显著,并探讨分析了相应的治疗方案,为针刺治疗AD提供理论指导。

Clinical Research Situation and Analysis of Acupuncture Compared with Western Medicine in Improving Cognitive Impairment and Behavioral and Psychological Symptoms in Patients with Alzheimer's Disease

Alzheimer''s disease (AD) is a neurodegenerative disease with hidden onset and progressive development. Clinical manifestations of AD patients are mainly cognitive impairment (CI) and behavioral and psychological symptoms (BPS), and may be accompanied by the disable activity of daily living and other symptoms. At present, western medicine therapy is the main treatment for AD patients, but this method can only delay the patient''s condition, and there are many side effects. According to the latest research, acupuncture therapy can improve the symptoms such as CI and BPS in AD patients. Therefore, in this paper, the literature on the improvement of CI and BPS in AD patients by acupuncture compared with western medicine in the past 25 years is reviewed, and the acupuncture methods, acupuncture points selection, treatment time and acupuncture effect are analyzed. It is found that acupuncture has a significant effect on CI and BPs in mild to moderate AD patients, and discusses and analyzes the corresponding treatment scheme, so as to provide theoretical guidance for acupuncture treatment of AD.