患者临床结局报告量表译评、建构及中医临床实践优化模式探讨＊

患者临床结局报告（PRO）侧重于近代心理学概念和策略,对目标受试者的主观体验、本体症状改善情况、以及疾患诊治满意程度予以综合评价;这过程所体现的“以人为本”思维与传统中医经典理论相吻合,故PRO在传统医学研究中日趋受到关注,是当前中医临证与效应评析至为关键的内容之一。本文围绕上述核心问题在PRO的定义及溯源、PRO的测评要点和价值、PRO量表的评译和泛文化编制、中医临床效应测评及PRO量表的应用、PRO量表的建构及中医临床实践模式优化等方面展开论述,并就PRO国外量表的引进及特性考评、中医PRO量表研制及评价等方面进行相关分析,以期为当前中医特色PRO量表研制及临床实践提供参考。

Study on Translation, Evaluation and Development of PRO Scales Involving Optimized Model of TCM Clinical Practice

The patient reported outcome (PRO) aims to evaluate the subjective experience of subjects, the improvement of subjects'' symptoms, the satisfaction degree of diagnosis and treatment of diseases, using the theory and strategies of modern psychology. During this process, people-oriented concept has been observed, which was consistent with the classical theory of traditional Chinese medicine (TCM). PRO has attracted increasing attention in TCM medical research, as well as being chosen as one of the key contents of current TCM clinical evidence and effect evaluation. Based on the core problem and principles, this paper attempted to discuss the issues such as the definition and sources of PRO, the measurement and meanings of PRO, interpretation and cross-cultural compilation of scales, application of PRO in TCM clinical effect assessment, construction of PRO and its model optimization in TCM clinical practice, etc., focusing on the introduction and evaluation of PRO scale abroad, the establishment and evaluation of TCM PRO scale, and so on. We hope that all these considerations can provide reference for better understanding of the development of PRO scale and TCM clinical practice.