| 双波长分光光度法测定复方盐酸麻黄碱滴鼻液含量 |
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| 引用本文： | 丁玉峰,颜德桥,艾正平. 双波长分光光度法测定复方盐酸麻黄碱滴鼻液含量[J]. 医药导报, 2002, 21(7): 436-437 |
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| 作者姓名： | 丁玉峰 颜德桥 艾正平 |
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| 作者单位： | 1. 华中科技大学同济医学院附属同济医院药学部,武汉,430030
2. 华中科技大学同济医学院药学院九八届,武汉,430030 |
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| 摘 要： | 目的:测定复方盐酸麻黄碱滴鼻液中盐酸麻黄碱和盐酸苯海拉明含量.方法:采用双波长紫外分光光度法测定,水作溶剂,选择盐酸麻黄碱和盐酸苯海拉明的测定波长对分别为257.0 nm/239.4 nm和230.0 nm/269.6 nm.结果:盐酸麻黄碱和盐酸苯海拉明的平均回收率分别为99.95%和99.37%,RSD分别为1.04%和0.67%.结论:该方法可用于复方盐酸麻黄碱滴鼻液的质量控制,适用于医院制剂的快速分析.
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| 关 键 词： | 双波长分光光度法 麻黄碱,盐酸 苯海拉明,盐酸 |
| 文章编号： | 1004-0781(2002)07-0436-02 |
| 修稿时间： | 2001-04-24 |
Determination of Element Content in Compound Ephedrine Hydrochloride Nasal Drops by Dual-wavelength Spectrophotometry |
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| DING Yu feng,YAN De qiao,AI Zheng ping. Determination of Element Content in Compound Ephedrine Hydrochloride Nasal Drops by Dual-wavelength Spectrophotometry[J]. Herald of Medicine, 2002, 21(7): 436-437 |
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| Authors: | DING Yu feng YAN De qiao AI Zheng ping |
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| Abstract: | Objective:To establish a method for determining the contents of ephedrine hydrochlorde and diphenydramine hydrochloride in nasal drops. Methods:A dual wavelength spectrophotometry was used to determine the element contents of compound ephedrine hydrochloride nasal drops. The wavelength sets of ephedrine hydrochloride and diphenydramine hydrochloride were at 257.0 nm/239.4 nm and 230.0 nm/269 nm, respectively. Results:The respective average recovery of ephedrine hydrochloride and diphenydramine hydrochloride were 99.95% and the RSD of them were 1.04% and 0.67%( n =5). Conclusion:The method we used was simple for hospital pharmacy. |
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| Keywords: | Dual wavelength spectrophotometry Ephedrine hydrochloride Diphenydramine hydrochloride |
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