| 一氧化氮及一氧化氮合酶在成年与老年大鼠前列腺中的变化 |
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| 引用本文： | 康灵斌.一氧化氮及一氧化氮合酶在成年与老年大鼠前列腺中的变化[J].现代医药卫生,2005,21(21):2885-2886. |
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| 作者姓名： | 康灵斌 |
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| 作者单位： | 丹阳市中医院外科,江苏,丹阳,212300 |
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| 摘 要： | 目的:研究一氧化氮(NO)及一氧化氮合酶(NOS)在成年与老年大鼠前列腺中的变化,探讨在大鼠前列腺老年化过程中的临床意义。方法:取4月龄及20月龄SD雄性大鼠各6只,分别取前列腺组织匀浆,检测其NO与NOS活性。结果:老年组大鼠的NO与NOS活性明显低于成年组(P<0.05)。结论:老年大鼠前列腺组织中NO水平及NOS活性的降低可能与前列腺良性增生及功能减退有关。
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| 关 键 词： | 前列腺 一氧化氮 一氧化氮合酶 大鼠 |
| 文章编号： | 1009-5519(2005)21-2885-02 |
| 收稿时间： | 2005-06-03 |
| 修稿时间： | 2005年6月3日 |
The change of nitric oxide and nitric oxide synthase in prostatic tissue in the grown and old rats |
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| KANG Ling-bin.The change of nitric oxide and nitric oxide synthase in prostatic tissue in the grown and old rats[J].Modern Medicine Health,2005,21(21):2885-2886. |
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| Authors: | KANG Ling-bin |
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| Institution: | Department of Surgery, Danyang Hospital of Tranditional Chinese Medicine,Jiangsu 212300,China |
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| Abstract: | Objective:To study the change of nitric oxide(NO) and nitric oxide synthase(NOS) in prostatic tissue in the grown and old rats.Methods:The level of NO and activity of NOS in prostatic tissue in the grown and old rats were measured respectively.Results:The level of NO and activity of NOS in prostatic tissue in the old rats were significantly lower than that in the grown rats(P<0.05).Conclusion:The results showed that the reduced level of NO and activity of NOS in prostatic tissue in the old rats could be associated with the hyperplasia and hypofunction of prostate. |
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| Keywords: | Prostate Nitric oxide Nitric oxide synthase Rat |
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