椎体终板形态与腰椎间盘突出关系的临床研究

背景:有研究报道,在间盘退变的过程中,可造成椎体终板的重塑.目前终板形态和椎间盘退变的关系仍不非常清楚.目的:观察分析椎体终板形态与腰椎间盘突出症的之间的关系.方法:纳入40例无腰椎疾病的正常人和62例腰椎间盘突出症患者,进行螺旋CT扫描,扫描范围从L4到S2,扫描条件:140 kV,345 mA,FOV160 mm,层厚1 mm,间距1.0.原始图像通过O2的三维重建图像工作站进行三维重建,W300,C80,ZOOM=1.5,Expand1.在平面重建术(CPR)基础上测量椎间盘最大前后,横径,圆形,面积和形状.结果与结论:终板形态和椎间盘突出症密切相关(P均＜0.01).终板面积和男性L4/5、男性和女性的L5/S1椎间盘突出关联差异无显著性意义(P＜0.05).提示椎体终板的边缘形状是腰椎的椎间盘突出症(L4/5、L5/S1)进展的重要因素之一.

Clinic research between vertebral endplate morphology and lumbar disc herniation

BACKGROUND: Studies demonstrated that vertebral endplate can be remodeled during intervertebral disc degeneration.However,the relationship between morphology of the vertebral endplate and intervertebral disc degeneration remains poorly understood.OBJECTIVE: To explore the relationship between the morphology of the vertebral endplate and the lumbar disc herniation.METHODS: Forty cases without previous spine disorder and sixty-two cases symptomatic lumbar disc herinations lumbar vertebral were scanned by using spiral CT.Scan range was from superior L4 to superior S2.Scan protocols as below: 140 kV,345 mAs,FOV 160 mm,layer of thick 1 mm,pitch 1.0.Original images were carried through three-dimensional reconstructions using O2 image work station,W300,C80,ZOOM=1.5,Expand 1.Intervertebral disc maximum anteroposterior,transverse diameter,circumference,area and shape were measured based on curve planar reconstruction.RESULTS AND CONCLUSION: Endplate shape was strongly related to disc herniation(all the P value < 0.01).Endplate area was a less significant factor L4/5 in men and L5/S1 in men and females(P < 0.05).The shape of the intervertebral body endplate margin is an important factor contributing to the development of disc herniation at L4/5 and L5/S1.