无创性指标预测食管静脉曲张的临床研究

目的 分析血小板计数/脾脏直径比值、心排血量在预测肝硬化食管静脉曲张存在及出血的价值.方法 收集2007年5月至2012年5月福建医科大学附属漳州市医院肝硬化住院患者63例,其中男41例、女22例,年龄40 ～63岁.按胃镜检查结果分为曲张组（44例）与非曲张组（19例）,出血组（36例）与非出血组（27例）,分析组间血小板计数/脾脏直径比值、心排血量.结果 曲张组与非曲张组之间血小板计数/脾脏直径比值（0.46±0.33 vs 0.50±0.31）、心排血量差异（4973.73±1315.04 vs 4673.08±1907.95）均无统计学意义（P〉0.05）,出血组与非出血组之间血小板计数/脾脏直径比值（0.37±0.24 vs 0.42±0.39）差异有统计学意义（P〈0.05）、心排血量（5397.99±1107.03 vs 4730.73±1763.28）差异无统计学意义（P〉0.05）.结论 血小板计数/脾脏直径比值在预测食管静脉曲张破裂出血上有一定价值.

Clinical Study of the Non-invasive Predictors for Cirrhotic Patients with Esophageal Varices

Objective To idenlify the clinical value nf plalelel enunt/splenic diameter and cardiac output fi）r the existence of esophageal varices and variees bleeding in cin＇hntic patients. Methods A cohort of 63 inpatients（ male 41 cases, female 22 cases, age 40-63 years）with liver cirrhosis within the latest five years in Zhangzhou Hospital Affiliated to Fujian Medical University during May 2007 and May 2012 was studied, including 44 patients of esophageal varices group and 19 patients of non-esophageal varices group,36 patients of bleeding group and 27 patients of non-bleeding group. The ratio of platelet count/splenic diameter and cardiac output were observed. Results There were no obvious differences for platelet count/splenic diameter ratio（0.46 _＋0.33 vs 0.50 -＋0.31 ） and cardiac output （4973.73 _＋ 1315.04 vs 4673.08 -＋ 1907.95 ） between esophageal varices group and non-esophageal varices group, platelet count/splenic diameter ratio （0.37 -＋ 0.24 vs 0.42 ＋ 0.39 ） was different between bleeding group and non-bleeding group, cardiac output （5397.99 ＋ 1107.03 vs 4730.73 ＋ 1763.28）was not different between bleeding group and non-bleeding group. Conclusion The ratio of platelet count/splenic diameter can be used as a non-invasive predictor for vafiees bleeding in cirrhotic patients.