肺癌患者抑郁症发生情况及相关危险因素Logistic回归分析

目的研究肺癌患者抑郁症发生情况及发生相关危险因素。方法采用症状自评量表（SCL-90）对河池市人民医院2009年3月至2012年3月收治的410例肺癌患者的心理情绪进行调查,对伴有抑郁症状的肺癌患者和未伴有抑郁症状的肺癌患者的临床资料进行对比分析,采用多因素非条件Logistic回归分析肺癌患者抑郁症的相关危险因素。结果 246例肺癌患者有抑郁症状,比例高达53.71%,经过单因素和多因素分析结果显示：女性（OR=5.864,95%CI 0.944~9.752）,文化程度较低（OR=4.362,95%CI 0.843~8.374）,家庭月收入〈2500元（OR=5.942,95%CI 0.458~9.953）,患病知情（OR=3.783,95%CI 0.753~8.358）,疼痛程度中度及以上（OR=3.456,95%CI0.353~11.836）,经过放化疗治疗（OR=4.342,95%CI 0.453~7.654）是肺癌患者发生抑郁的相关危险因素。结论对于具有上述危险因素的患者应当进行积极的心理干预,以减少肺癌患者抑郁症的发生。

Occurrence Risk Factors Logistic Regression Analysis of Depression Lung Cancer

Objective To investigate the risk factors of depression occurrence in lung cancer patients. Methods Symptom checklist（ SCL-90） was used to investigate psychological emotions of 410 cases of lung cancer admitted to the First People＇s Hospital of Hechi from Mar. 2009 to Mar. 2012,and the clinical data of lung cancer patients with depressive symptoms and without depressive symptoms were compared multivariate unconditional Logistic regression analysis was done for depression in lung cancer patients. Results 246 lung cancer patients had depressive symptoms,which was a high proportion of 53. 71%,after single and multiple factors analysis results showed that： female（ OR = 5. 864,95% CI： 0. 944-9. 752）,lower cultural level（ OR = 4. 362,95% CI： 0. 843-8. 374）,family monthly income 2500 Yuan（ OR = 5. 942,95% CI： 0. 4589. 953）,the prevalence of informed（ OR = 3. 783,95% CI： 0. 753-8. 358）,pain severity moderate and above（ OR =3. 456,95% CI： 0. 353-11. 836）,after chemoradiation therapy（ OR =4.342,95% CI： 0. 453-7.654） were related risk factors for depression in lung cancer patients. Conclusion Lung cancer patients with above mentioned risk factors should be given positive psychological interventions to reduce the incidence of depression.