阻塞性睡眠呼吸暂停综合征并发勃起功能障碍的机制及治疗

勃起功能障碍（ED）是男科的常见病,阻塞性睡眠呼吸暂停综合征（OSAS）常伴有ED,两者关系密切.OSAS并发ED的最重要的原因可能为OSAS患者的血管顺应性降低和慢性间歇性缺氧引起血管内皮功能障碍.在积极治疗OSAS的基础上,使用抗氧化剂、5型磷酸二酯酶抑制剂等保护阴茎血管内皮功能可以有效改善勃起功能,将成为治疗勃起功能障碍的新方向.

Mechanism and Treatment of Obstructive Sleep Apnea Syndrome Complicated with Erectile Dysfunction

Erectile dysfunction （ED）is a common male disease, while obstructive sleep apnea syndrome （OSAS） is often accompanied by the occurrence of ED, indicating the two are closely related. The most important cause of ED complicated with OSAS may be reduced vascular compliance and chronic intermittent hypoxia-induced endothelial dysfunction. On the basis of active treatment of OSAS, the use of antioxidants, PDE5 inhibitors can protect the penile vascular endothelial function effectively and thus improve erectile function,which will become a new direction for the treatment of ED.