Household survey of dengue infection in central Brazil: spatial point pattern analysis and risk factors assessment |
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Authors: | Siqueira João B Martelli Celina M T Maciel Ivan J Oliveira Renato M Ribeiro Maria G Amorim Flúvia P Moreira Bruno C Cardoso Divina D P Souza Wayner V Andrade Ana Lúcia S S |
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Affiliation: | Brazilian Ministry of Health, 7o Andra Sala 715 70 070, 040 Brasilia, DF, Brazil. |
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Abstract: | Urban dengue fever is now considered a major public health threat in most American countries. A household survey was conducted in the city of Goiania in central Brazil in 2001 to assess prevalence of dengue infection and individual and area-based risk factors. Spatial point pattern analysis was performed using the dual Kernel method. A total of 1,610 households were surveyed; 1,585 individuals more than five years old had blood and data collected. Sera were tested for IgM/IgG antibodies by an enzyme-linked immunoassay. Area-based indicators derived from census data were linked to geocoded residential address. The seroprevalence of dengue was 29.5% and the estimate prevalence surface reached 50% in the outskirts areas. The risk of infection was significantly associated with older age (P < 0.01), low education (odds ratio [OR] = 3.45, 95% confidence interval [CI] = 1.82-6.55), and low income (OR = 1.32, 95% CI = 1.02-1.71) in multivariate analysis. This study highlighted the heterogeneity of dengue transmission within the city and can assist in spatial targeting control interventions. |
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