贵阳城区成人维生素D营养状况调查

目的 调查贵阳城区成人维生素D营养状况.方法 用整群抽样的方法抽取贵阳市云岩区 宅吉社区中20～79岁(年龄中位数为45.2岁)健康成人1 500名,于2009年11月至2010年2月进行问卷调查,并采集清晨空腹静脉血分离血清,用美国DiaSorin公司的放射免疫试剂盒测定血清25-羟维生素D25(OH)D]水平.结果 贵阳城区成人血清25(OH)D平均水平为(20.4±9.0)ng/ml;成人25(OH)D缺乏25(OH)D＜20ng/ml]、不足20ng/ml≤25(OH)D＜30 ng/ml]、正常25(OH)D≥30 ng/m1]分别为52.3%、32.3%及15.4%.贵阳城区青年、中年、老年人群血清25(OH)D平均水平依次为(18.2±9.2)、(22.8±8.7)及(19.9±7.8)ng/ml.青年、中年与老年人群维生素D缺乏依次为62.8%、40.2%与55.4%.高学历人群(≥13年)维生素D缺乏为61.6%,低体重人群(体重指数＜18.5 kg/m2)维生素D缺乏为64.4%.结论 贵阳城区成人维生素D缺乏普遍,尤其见于老年人及青年人群,并受文化程度、年龄、吸烟等因素影响.

Abstract：

Objective To evaluate vitamin D status in healthy adults living in Guiyang. Method 1 500 healthy volunteers aged 20-79 years ( mean 45.2 years ) were recruited from a community in Guiyang by cluster sampling method. Questionnaires for living habits and fasting blood samples were collected from November, 2009 to February, 2010. Serum 25 ( OH ) D concentrations were measured by radioimmunoassay, using the DiaSorin kit,USA. Results The average serum 25 ( OH ) D level was ( 20. 4±9.0 ) ng/ml. The percentages of vitamin D deficiency 25 ( OH ) D ＜ 20 ng/ml], insufficiency 20 ng/ml ≤ 25 ( OH ) D ＜ 30 ng/ml], and sufficiency 25 ( OH ) D ≥ 30ng/ml] were 52. 3% , 32. 3% , and 15.4% , respectively. The 25 (OH) D concentrations in the young, middle-aged,and elderly were ( 18. 2±9. 2), (22. 8±8. 7), and ( 19. 9±7.8) ng/ml, respectively. The percentages of vitamin D deficiency in these groups were 62. 8%, 40. 2%, and 55.4%, being 61.6% in higher educational group ( ≥ 13 years) and 64. 4% in the group with lower body mass index ( ＜ 18.5 kg/m2 ). Conclusion Vitamin D deficiency is common in Guiyang including all age groups, especially among the youth and the elderly. Serum 25-hydroxyvitamin D level is also influenced by education, age, smoking, and other factors.

Vitamin D status in healthy adults in Guiyang of China

Objective To evaluate vitamin D status in healthy adults living in Guiyang. Method 1 500 healthy volunteers aged 20-79 years ( mean 45.2 years ) were recruited from a community in Guiyang by cluster sampling method. Questionnaires for living habits and fasting blood samples were collected from November, 2009 to February, 2010. Serum 25 ( OH ) D concentrations were measured by radioimmunoassay, using the DiaSorin kit,USA. Results The average serum 25 ( OH ) D level was ( 20. 4±9.0 ) ng/ml. The percentages of vitamin D deficiency 25 ( OH ) D ＜ 20 ng/ml], insufficiency 20 ng/ml ≤ 25 ( OH ) D ＜ 30 ng/ml], and sufficiency 25 ( OH ) D ≥ 30ng/ml] were 52. 3% , 32. 3% , and 15.4% , respectively. The 25 (OH) D concentrations in the young, middle-aged,and elderly were ( 18. 2±9. 2), (22. 8±8. 7), and ( 19. 9±7.8) ng/ml, respectively. The percentages of vitamin D deficiency in these groups were 62. 8%, 40. 2%, and 55.4%, being 61.6% in higher educational group ( ≥ 13 years) and 64. 4% in the group with lower body mass index ( ＜ 18.5 kg/m2 ). Conclusion Vitamin D deficiency is common in Guiyang including all age groups, especially among the youth and the elderly. Serum 25-hydroxyvitamin D level is also influenced by education, age, smoking, and other factors.