| 注射用加替沙星与注射用头孢拉定的配伍稳定性考察 |
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| 引用本文： | 杨继章,杨树民,刘瑞琴,柳俊颖. 注射用加替沙星与注射用头孢拉定的配伍稳定性考察[J]. 中国药房, 2005, 16(13): 1015-1017 |
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| 作者姓名： | 杨继章 杨树民 刘瑞琴 柳俊颖 |
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| 作者单位： | 1. 河北医科大学附属第一医院药剂科,石家庄市,050031
2. 河北医科大学药学院,石家庄市,050017 |
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| 基金项目： | 河北省医学科学研究重点项目 |
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| 摘 要： | 目的:考察注射用加替沙星与注射用头孢拉定分别在5%葡萄糖注射液和0.9%氯化钠注射液中的配伍稳定性。方法:分别观察及测定配伍液在室温下放置8h内的外观及pH值变化,并用紫外分光光度法测定其含量。结果:两药配伍后,外观无明显变化,而pH值及含量变化很大。结论:注射用加替沙星与注射用头孢拉定存在配伍禁忌。
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| 关 键 词： | 加替沙星 头孢拉定 配伍 稳定性 紫外分光光度法 |
| 文章编号： | 1001-0408(2005)13-1015-03 |
| 修稿时间： | 2004-09-09 |
Study on the Compatibility of Gatifloxacin for Injection with Cefradine for Injection |
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| YANG Jizhang,Yang Shumin,LIU Ruiqin,Liu Junying. Study on the Compatibility of Gatifloxacin for Injection with Cefradine for Injection[J]. China Pharmacy, 2005, 16(13): 1015-1017 |
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| Authors: | YANG Jizhang Yang Shumin LIU Ruiqin Liu Junying |
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| Abstract: | OBJECTIVE:To observe the compatibility of gatifloxacin for injection with cefradine for injection in 5% glucose injection and in 0.9% sodium chloride injection respectively.METHODS:At room temperature for8hours the change in appearance and pH value were observed,while the content was determined by UV spectrophotometry as well.RESULTS:There was no evident change in appearance after the mixture,but the pH value and concentration changed significantly.CONCLUSIONS:There exists incompatibility between gatifloxacin for injection and cefradine for injection. |
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| Keywords: | Gatifloxacin Cefradine Compatibility Stability UV spectrophotometry |
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