老年人冠状动脉介入术后造影剂对肾功能的影响

目的 了解造影剂对老年人冠状动脉介入诊疗术后肾功能的影响.方法 选择经皮冠状动脉介入治疗的老年患者40例,年龄(70.5±8.2)岁.全部选用低渗非离子造影剂,接受水化治疗(静脉水化).测定造影前、造影后第1 d、第3 d、第7 d肾功能指标.结果 尿α1微球蛋白术后第1 d、第3 d分别为(14.74±14.58)m...

The Effection of Contrast Agent on Renal Function after Percutaneous Coronary Intervention in Elderly

Objective To understand the renal function influcence of contrast agent after coronary interventional therapy in elderly.Methods 40 elderly cases who were adopted percutaneous coronary intervention were studied.The mean age was 70.5±8.2 years.Low permeability and non-ionic contrast agent were selected to used.Hydration treatment were perfromed before treatment.Renal function was detected before angiography,1 d,3 d and 7 d post angiography.Results The urinary α1-microglobulin was(14.74±14.58)mg/L and 13.86±18.09 mg/L in 1 d and 3 d postoperative respectively,and there were significant Increased contrast with before angiography(6.71±5.11)mg/L(P<0.05).However the level returned preoperative level in 7d after angiographt.blood urea nitrogen,creatinine,urinary albumin,urinary transferrin,IgG and preoperative urine were no significant difference contrast with before angiography.There only 1 case was diagnosed contrast nephropathy(2.5%) with diagnostic standards.Conclusion To choice contrast agent with less renal toxicity and hydration treatment can significantly reduce the incidence of contrast nephropathy,even if renal functional lession occured,renel function will recovered to normal after 1 week.