| 不同剂量的黄芪桂枝五物汤加减治疗糖尿病周围神经病变患者的对比研究 |
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| 引用本文： | 宋凤林,贾锐馨,李国永,王彩娟,马慧娟.不同剂量的黄芪桂枝五物汤加减治疗糖尿病周围神经病变患者的对比研究[J].中医杂志,2011,52(7):570-571,581. |
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| 作者姓名： | 宋凤林 贾锐馨 李国永 王彩娟 马慧娟 |
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| 作者单位： | 1. 赵县中医院内一科,河北省赵县平棘大街66号,051530
2. 河北省人民医院内分泌二科 |
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| 基金项目： | 河北省科技支撑计划项目 |
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| 摘 要： | 目的比较不同药物剂量的黄芪桂枝五物汤加减治疗糖尿病周围神经病变(DPN)患者的临床疗效。方法将68例DPN患者随机分为观察组和对照组各34例,两组均给予基础治疗及黄芪桂枝五物汤加减,其中对照组药物剂量按1两等于9g计算;观察组药物剂量按1两等于15g,两组均每日1剂,连用8周。于治疗前后分别检测肝肾功能及腓神经传导速度(NCV)变化,并判定临床疗效。结果观察组总有效率为91.2%,对照组总有效率为70.6%,两组比较差异有统计学意义(P<0.01);两组患者治疗后NCV均较治疗前明显提高,差异有统计学意义(P<0.05),治疗后两组间比较差异亦有统计学意义(P<0.05);两组患者治疗前后均无肝、肾功能异常及其他不良反应。结论药物剂量按1两等于15g换算的黄芪桂枝五物汤加减可明显提高DPN的临床疗效,并优于药物剂量按1两视为9g计算,而且未见明显毒副作用。
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| 关 键 词： | 糖尿病周围神经病变 黄芪桂枝五物汤 剂量 腓神经传导速度 |
Comparative Study on the Effect of Huangqi Guizhi Wuwu Decoction in Different Dosages on Diabetics with Peripheral Neuropathy |
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| SONG Fenglin,JIA Ruixin,LI Guoyong,WANG Caijuan,MA Huijuan.Comparative Study on the Effect of Huangqi Guizhi Wuwu Decoction in Different Dosages on Diabetics with Peripheral Neuropathy[J].Journal of Traditional Chinese Medicine,2011,52(7):570-571,581. |
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| Authors: | SONG Fenglin JIA Ruixin LI Guoyong WANG Caijuan MA Huijuan |
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| Institution: | SONG Fenglin1,JIA Ruixin1,LI Guoyong1,WANG Caijuan1,MA Huijuan2(1.TCM Hospital of Zhaoxian County,Hebei Province 051530,2.Hebei Provincial People's Hospital) |
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| Abstract: | Objective To observe the therapeutic effect of Huangqi Guizhi Wuwu Decoction(Decoction of Five Materials including Radix Astragali seu Hedysari and Ramulus Cinnamomi)in different dosages on diabetics with peripheral neuropathy(DPN).Methods Sixty-eight DPN patients were randomized into treatment group and control group with 34 in each.Both groups were given the decoction based on routine methods.The control group was administered Huangqi Guizhi Wuwu Decoction in a dosage with 1 Liang as 9g,while the treatmen... |
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| Keywords: | diabetics with peripheral neuropathy(DPN) Huangqi Guizhi Wuwu Decoction(Decoction of Five Materials including Radix Astragali seu Hedysari and Ramulus Cinnamomi) dosage peroneal nerve conduction velocity |
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