Evaluation of 13C-urea breath test and fecal antigen immunoassay to detect Helicobacter pylori infection in Gambian infants |
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Authors: | Jones Rhys T Darboe Momodou K Doherty Conor P MacKay William G Weaver Lawrence T Campbell David I Thomas Julian E |
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Institution: | University of Newcastle, School of Clinical Medical Sciences, Newcastle-upon-Tyne, UK. |
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Abstract: | Helicobacter pylori colonization was measured by 13C]-urea breath test in 198 Gambian infants and by fecal enzyme-linked immunosorbent assay in 52 of the 198 at ages 2, 5, and 12 months. By 12 months there was good concordance between tests; 33 of 44 (75%) test results were positive by enzyme-linked immunosorbent assay, and 29 of 44 (66%) test results were positive by urea breath test. H. pylori colonization is common among Gambian infants, and noninvasive tests can provide a reliable means of diagnosis. |
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