影響NAION中心視力的因素及療效評價

目的探討非動脉炎性前部缺血性視神經病變(nonarteritic anteriorischemic optic neuropathy,NAION)影響中心視力的因素及治療效果,以利于療效評定及預後判斷.方法240例NAION患者(160例接受住院治療)的臨床資料,從中心視力、水腫程度、缺血部位、視野、FFA檢查等方面進行統計分析.結果240例NAION患者中心視力的損害程度,在不同缺血部位、水腫程度之間有顯著的差异(P＜0.005).160例患者住院治療,視盤水腫消退時間最長為35天,最短11天,平均時間21.5天,中心視力提高者104例,穩定者52例,有效率為97.5%,視野改善者134例,有效率為83.8%,FFA造影復查缺血改善者141例,有效率為88.1%.結論影NAION中心視力的重要因素是缺血部位、水腫程度,積極針對性的治療對防止NAION致盲有重要意義.

The cause and the effects of visual acuity on nonarteritic anterior ischemic optic neuropathy

Objective To investigate the cause and the effects of visual acuity on nonarterteritic anterior ischemic optic neuropathy (NAION) for accessing. Methods 240 cases of NAION were analyzed in visual acuity, optic disc ischemia, degree of edema, visual field, fundus fluorescence angiography (FFA). Results 240 cases with NAION associated with ischemic area and edema in optic disc significantly. The longest duration of optic disc edema diminished in 160 patients was 35 days, the shortest 11 days (means 21.5 days) after treatment. The visual acuity was improved in 104 patients (effective rate 97.5%), visual field was improved in 134 patients (effective rate 83.8%), ischemia reduced in 141 patients (effective rate 88.1% ) according to FFA. Conclusion The study showed that the factors affecting the vision of NAION patients are ischemic area and edema in optic dies. Actively treatment and prevention to NAION is very important.