康复新液促进高位肛周脓肿置管引流术后创面愈合的临床研究

目的观察康复新液促进高位肛周脓肿置管引流术后创面愈合的临床疗效。 方法将天山中医医院肛肠科从2015年7月至2017年6月诊断为高位肛周脓肿的住院患者60例按照入院顺序随机分为治疗组30例和对照组30例，均采用高位肛周脓肿置管引流术。术后第2 d起，治疗组在换药时应用康复新冲洗脓腔，对照组应用甲硝唑液冲洗脓腔，比较两组术后拔除引流管时间、创面完全愈合时间、术后第3 d、7 d、14 d肛门疼痛和脓腔渗液情况，术后1个月总有效率、随访半年的脓肿复发率及成瘘率。 结果治疗组的拔引流管时间（t=3.506，P=0.001）、创面完全愈合时间（t=6.64，P<0.001）明显短于对照组，差异均有统计学意义；两组间在术后第3 d的疼痛评分（H=0.182，P=0.670）和渗液评分（H=0.001，P=0.973）的差异无统计学意义；在术后第7 d、14 d疼痛评分（H=4.480，P=0.034；H=4.516，P=0.034）和渗液评分（H=5.263，P=0.022；H=4.345，P=0.037）的差异均有统计学意义。术后1个月的总有效率治疗组（93.3%）明显优于对照组（73.3%），差异有统计学意义（χ²=4.320，P<0.05）；随访半年，两组复发病例均只有1例，差异无统计学意义（χ²=0.000，P>0.05）；明确形成肛瘘的病例中，治疗组（6.7%）明显少于对照组（30%），差异有统计学意义（χ²=5.455，P<0.05）。 结论康复新液可加快高位肛周脓肿置管引流术后创面愈合速度，减少渗液，减轻疼痛，疗效显著，具有临床使用价值。

Clinical research on Kangfuxin liquid in promoting postoperative wound healing of catheter drainage with high anal abscess

ObjectiveTo observe clinical effect of Kangfuxin liquid to promoting postoperative wound healing of catheter drainage with high anal abscess. MethodsSixty patients of high perianal abscess hospitalized in Shanghai Changning Tianshan Hospital of Traditional from July 2015 to June 2017 were divided into treatment group and control group according to the digital random table method. Both of the two groups were treated by the catheter drainage. The treatment group use Kangfuxin liquid to wash abscess cavity from the 2nd day after operation while the control group use metronidazole liquid. Compare the extubation time, wound healing time,anal pain and exudation in the 3rd, 7th, 14th day after operation, the total effective rate after one month, the recurrence rate and the rate of anal fistula formation after six months. ResultsThe treatment group need less extubation time (t=3.506, P=0.001) and wound healing time (t=-6.64, P<0.001) than the control group, with statistically significant differences. The scores of anal pain (H=0.182, P=0.670) and exudation(H=0.001, P=0.973) in the 3rd day after operation has no significant difference. The pain scores (H=4.480, P=0.034; H=4.516, P=0.034) and the exudation scores (H=5.263, P=0.022; H=4.345, P=0.037) of the treatment group are less than the control group after the 7th, 14th day after operation, with statistically significant differences. The total effective rate after one month of the treatment group (93.3%) was significantly higher than that of the control group (73.3%) (χ²=4.320, P<0.05). Followed up for six months, both of the two groups has one case recurrent perianal abscess, with no significant differences (χ²=0.000, P>0.05), and the anal fistula formation in the treatment group (6.7%) is much less than the control group (30%) with significant differences (χ²=5.455, P<0.05). ConclusionKangfuxin liquid can promote postoperative wound healing of catheter drainage with high anal abscess, produce anal pain and exudation. It is validity and worthy of clinic application.