某大学本科生对HPV及疫苗认知及接种意愿的分析

目的 调查广州某大学本科学生对 HPV 疫苗认知情况及 HPV 疫苗接种意愿,分析其影响因素,为日后 HPV 疫苗在国内推广提供建议。方法 调查方式采用自行设计调查问卷,进行现场调查,研究对象问卷自填式,并做好质量监控,获得某大学本科学生共 579 名。内容包括基本情况及人口统计学特征、对 HPV 疫苗和相关疾病的认知情况以及 HPV 疫苗接种的意愿。结果 共获得 579 有效问卷,有效率为 96.5%,有 42.3%的人听说过 HPV 疫苗,有 21.7%的人愿意自己接种疫苗。性别差异对 HPV 的了解有统计学意义(P<0.05),年级方面,除了大三、大四及以上2组之外,其余各组对 HPV 认知差异有统计学意义(P<0.05),而生源地方面除了大陆-澳门和澳门-台湾之外,各生源地包括香港-澳门、香港-台湾、香港-大陆和大陆-台湾组对 HPV 认知差异有统计学意义(P<0.05)。是否听说HPV 相关疾病、是否担心患 HPV 相关疾病、疫苗的可接受价格和是否有过妇科病史对 HPV 疫苗的接种意愿存在差异(P<0.05),而性别、民族、生源地、年级等对于 HPV 疫苗的接种意愿的差异无统计学意义(P>0.05)。结论 大陆的高年级女性对 HPV 疫苗了解的程度较高。对于 HPV 疫苗接种,女性以及亲戚或朋友有过妇科病史的人更愿意接种 HPV 疫苗,对国产疫苗可接受价格在 1 000～3 000 元的人具有注射疫苗的倾向,不担心患宫颈癌的人更多地倾向于不接种HPV 疫苗。

Knowledge and intention of students in a university regarding human papillomavirus and its vaccine

Objective To investigate the knowledge and intention of the students in a university regarding human papillomavirus (HPV) and its vaccine and analyze the influencing factors. Methods Across-sectional field survey was performed with the self-designed questionnaire, and the objects were 579 undergraduate students of auniversity. The content of questionnaire included the questions about the socio-demographic information, knowledge and beliefs about HPV as well as participants’ intention to be vaccinated. Results A total of 579 valid questionnaires were obtained, with an effective rate of 96.5%. About 42.3% of the participants (n=245) had heard of HPV and 21.7% of them indicated that they would likely be vaccinated. There was a significant difference between different sex groups (P<0.05), and there was a significant difference among the grade groups expect the juniority and seniority in the knowledge of HPV.There were significant differences (P<0.05) in the cognition of HPV between the two places of origin including Hong Kong and Macao, Hong Kong and Taiwan, Hong Kong and Mainland China, and Taiwan and Mainland China, except Mainland China and Macao, and Macao and Taiwan.Whether they heard of HPV-related diseases, worrying about the risk of HPV-related diseases, the acceptable price of vaccines, and whether there was a gynecological history had significant influences on the HPV vaccination will (P<0.05).For the willing of HPV vaccination, there was no statistically significant difference (P>0.05) between/among the different genders, ethnicities, places of originand grades. Conclusion The senior female students in Mainland China have a higher level of knowledge about the HPV vaccination. For HPV vaccination, the women whose relatives or friends have a gynecological history are more willing to be inoculated. The acceptable price of domestic vaccines is 1000-3000 yuan in the people with the tendency of vaccination. The students without the worry about suffering from cervical cancer more tend to not inoculate HPV vaccines.