TURP术前停用阿司匹林的时间选择

目的 探讨术前长期服用阿司匹林的良性前列腺增生患者在行经尿道前列腺切除术(TURP)前停用阿司匹林的最佳时间。方法 选取2011年10月至2015年12月间,长期服用阿司匹林并在我科行TURP治疗的良性前列腺增生患者181例;根据术前停用阿司匹林的时间分为停药7d组(60例)、停药10d组(61例),另选60例同期未服用阿司匹林的良性前列腺增生患者作为对照组。回顾性分析比较三组前列腺体积、住院时间、术后住院时间、手术持续时间、术中及术后出血量、术中及术后输血例数、术后膀胱冲洗时间、尿管拔除时间、围手术期心脑血管并发症等指标。结果 停药7d组、停药10d组与对照组患者之间的手术持续时间、术中及术后出血量、术后膀胱冲洗时间、尿管拔除时间、术后住院时间无显著统计学差异(P>0.05)。所有患者围手术期均未发生严重心脑血管事件,无死亡病例。结论 在严格把握适应证和禁忌证的前提下,对于长期服用阿司匹林的良性前列腺增生患者,TURP术前停用阿司匹林7d是安全可行的。

The timing selection of stopping aspirin before transurethral resection of the prostate

Objective To investigate the best time of stopping aspirin before transurethral resection of the prostate (TURP) in patients with benign prostatic hyperplasia (BPH) who preoperative long-term use of aspirin. Methods From October 2011 to December 2015, 181 patients with BPH who preoperative long-term use of aspirin treated by TURP in our department were selected. According to the time of stopping aspirin before operation, the patients were divided into 7 days group (60 cases) and 10 days group (61 cases). Another 60 BPH patients who did not take aspirin meanwhile were selected as control group. The volume of prostate, hospitalization time, postoperative hospitalization time, operative duration, intraoperative and postoperative blood loss, intraoperative and postoperative blood transfusion, postoperative bladder irrigation time, urinary catheter extraction time, perioperative cardiovascular and cerebrovascular complications were retrospectively analyzed and compared among these three groups. Results There were no significant difference in the duration of operation, the amount of blood lost during and after operation, the time of bladder irrigation, the time of extubation of urinary tube and the time of hospitalization after operation (P>0.05) among 7 days, 10 days and control group. No serious cardiovascular and cerebrovascular events occurred in all patients during perioperative period. No deaths occurred. Conclusion Under the condition of strict indication and contraindication, it is safe and feasible to stop aspirin for 7 days before TURP in patients with BPH who long-term use of aspirin.