| 低剂量化疗作用机制的研究进展 |
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| 引用本文： | 梁语丝,谭永刚,邹华伟 审校. 低剂量化疗作用机制的研究进展[J]. 实用肿瘤学杂志, 2017, 31(6): 538-542. DOI: 10.11904/j.issn.1002-3070.2017.06.011 |
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| 作者姓名： | 梁语丝 谭永刚 邹华伟 审校 |
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| 作者单位： | 中国医科大学附属盛京医院肿瘤科(沈阳 110022) |
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| 基金项目： | 国家自然科学基金资助项目(81472806) |
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| 摘 要： | 化疗是肿瘤综合治疗的主要方式之一,多年来在肿瘤治疗中发挥着重要作用。但近年来低剂量化疗(Low-dose chemotherapy)利用其化疗药物的作用点,采取合理的给药方式和计划,且相对于最大耐受剂量化疗具有毒副反应小、患者耐受性明显提高、疗效更佳等优势,已逐渐成为临床中常用的治疗策略。本文就低剂量化疗的作用机制的研究进展做一系统综述。
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| 关 键 词： | 低剂量化疗 抗血管生成 细胞凋亡 |
| 收稿时间： | 2017-06-11 |
Research progress on mechanism of low-dose chemotherapy |
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| LIANG Yusi,TAN Yonggang,ZOU Huawei. Research progress on mechanism of low-dose chemotherapy[J]. Journal of Practical Oncology, 2017, 31(6): 538-542. DOI: 10.11904/j.issn.1002-3070.2017.06.011 |
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| Authors: | LIANG Yusi TAN Yonggang ZOU Huawei |
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| Affiliation: | Department of Oncology,Shengjing Hospital of China Medical University,Shenyang 110022,China |
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| Abstract: | Chemotherapy is one of the main ways for comprehensive treatment of tumors,and has played an important role in tumor treatment for many years.However,in recent years,low-dose chemotherapy(Low-dose chemotherapy) has gradually become a clinical treatment strategy commonly used to taken a reasonable mode of administration and planning,relative to the maximum tolerated dose of chemotherapy with small side effects,patient tolerance significantly improved,better efficacy and other.In this paper,the mechanism of low-dose chemotherapy on the progress is reviewed systematicly. |
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| Keywords: | Low-dose chemotherapy Anti-angiogenesis Cell apoptosis |
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