去乙酰毛花苷注射液联合酒石酸美托洛尔治疗急性左心衰伴快速心室率心房颤动患者的效果分析

目的研究去乙酰毛花苷注射液联合酒石酸美托洛尔治疗急性左心衰伴快速心室率心房颤动的效果。 方法选取2016年5月至2017年3月胶州市人民医院收治的74例急性左心衰伴快速心室率心房颤动患者，依照治疗方案分为观察组和对照组，各37例。在常规治疗基础上，对照组接受去乙酰毛花苷注射液治疗，观察组接受去乙酰毛花苷注射液＋酒石酸美托洛尔治疗。比较两组疗效，治疗前后心室率、QT间期、心功能指标心排血量(CO)、左心室射血分数(LVEF)]。 结果观察组治疗有效率94.59%(35/37)高于对照组72.97%(27/37)，差异有统计学意义(P<0.05)。治疗后两组QT间期对比，差异无统计学意义(P>0.05)，观察组心室率低于对照组(P<0.05)。治疗后观察组LVEF、CO高于对照组(P<0.05)。 结论去乙酰毛花苷注射液联合酒石酸美托洛尔治疗急性左心衰伴快速心室率心房颤动效果显著，能有效恢复患者心室率，改善心功能。

Effect of deslanoside injection combined with metoprolol tartrate on patients with acute left heart failure and atrial fibrillation with rapid ventricular rate

ObjectiveTo investigate the effect of deslanoside injection combined with metoprolol tartrate on patients with acute left heart failure and atrial fibrillation with rapid ventricular rate. MethodsSeventy-four patients with acute left heart failure and atrial fibrillation with rapid ventricular rate treated in Jiaozhou People's Hospital from May of 2016 to March of 2017 were selected and divided into control group and observation group, 37 cases in each group. On the basis of routine treatment, the control group was treated with deslanoside injection, while the observation group was treated with deslanoside injection combined with metoprolol tartrate. The curative effect, ventricular rate, QT interval and cardiac function, including cardiac output (CO) and left ventricular ejection fraction (LVEF) before and after treatment were compared between the two groups. ResultsThe effective rate of observation group was 94.59% (35/37), higher than that of control group 72.97% (27/37), and the difference was statistically significant (P<0.05). There was no significant difference in QT interval between the two groups after treatment (P>0.05). The ventricular rate of the observation group was lower than that of the control group (P<0.05). After treatment, the LVEF and CO in the observation group were higher than those in the control group (P<0.05). ConclusionDeslanoside injection combined with metoprolol tartrate has a significant effect in the treatment of acute left heart failure with rapid ventricular rate atrial fibrillation, can effectively restore the patient's ventricular rate, improve cardiac function.