胸痛中心建设对急性ST段抬高型心肌梗死患者PPCI介入治疗预后的影响

目的研究胸痛中心建设对急性ST段抬高型心肌梗死(STEMI)患者急诊经皮冠状动脉介入(PPCI)治疗预后的影响。 方法选取晋城市人民医院胸痛中心建设前1 a收治的73例STEMI患者作为对照组，胸痛中心建设后8个月收治的95例STEMI患者作为观察组，两组患者均接受PPCI治疗，比较两组进门至球囊扩张(D－to－B)时间、住院期间心力衰竭发生率及术后6个月6 min步行试验距离(6－MWT)。 结果对照组D－to－B时间为(122.24±36.05)min，观察组为(73.15±22.38)min，两组比较，差异有统计学意义(P<0.05)。对照组住院期间心力衰竭发生率为21.92%(16/73)，观察组住院期间心力衰竭发生率为8.42%(8/95)，两组心力衰竭发生率比较，差异有统计学意义(P<0.05)。对照组患者术后6个月6－MWT为(398.15±63.11)m，观察组为(486.02±56.30)m，两组术后6个月6－MWT比较，差异有统计学意义(P<0.05)。 结论胸痛中心建设应用于STEMI患者治疗中，可明显缩短D－to－B时间，减少住院期间心力衰竭，改善预后。

Effect of chest pain center construction on prognosis of patients with acute ST-segment elevation myocardial infarction undergoing PPCI

ObjectiveTo study the effect of chest pain center construction on prognosis of patients with acute ST-segment elevation myocardial infarction (STEMI) undergoing direct percutaneous coronary intervention (PPCI). MethodsSeventy-three patients with STEMI treated in one year before the construction of chest pain center were enrolled as the control group. Ninety-five patients with STEMI treated in eight months after the construction of chest pain center were enrolled as observation group. Both groups were treated with PPCI. The portal to balloon dilatation (D- to-B) time, incidence of heart failure during hospitalization, and 6-minute walking test distance (6-MWT) in six months after operation were compared between two groups. ResultsThe D-to-B time in control group was (122.24±36.05) min, while it is (73.15±22.38) min in observation group, and there was a statistical difference between two groups (P<0.05). The incidences of heart failure during hospitalization in control group and observation group were 21.92%(16/73) and 8.42%(8/95) respectively, and the difference was sitatistically significant (P<0.05). 6-MWT in six months after operation was (398.15±63.11) m in control group and (486.02±56.30) m in observation group, and the difference was sitatistically significant (P<0.05). ConclusionThe construction of chest pain center is suitable for the treatment of STEMI patients, which can significantly shorten the D-to-B time, reduce heart failure during hospitalization, and improve the prognosis.