杏芎氯化钠注射液对脑梗死患者肢体运动功能的疗效研究

目的观察分析杏芎氯化钠注射液对脑梗死患者肢体运动功能恢复的疗效。 方法选取广州医科大学附属第五医院神经康复科自2018年2月至10月住院的200例脑梗死患者，随机分组，试验组103例，对照组97例。对照组予以标准脑梗死二级预防治疗及神经康复治疗，试验组则在对照组治疗的基础上加用杏芎氯化钠注射液治疗，采用Brunnstrom分期及简化Fugle-Meyer评分评定2组患者治疗前后的运动功能。 结果从Brunnstrom分期角度分析，试验组和对照组治疗14 d后手、上肢、下肢运动功能与治疗前比较均有改善，差异具有统计学意义（P<0.05）。从Fugle-Meyer评分角度分析，试验组Fugle-MeyerⅠ级、Ⅱ级患者65例，治疗后25例肢体功能评估为Ⅲ级；对照组Fugle-MeyerⅠ级、Ⅱ级患者62例，治疗后14例患者肢体功能评估为Ⅲ级；试验组疗效高于对照组，差异具有统计学意义（P=0.046）。 结论试验组、对照组的疗法对脑梗死患者肢体运动功能均有全面而明显的改善作用。在标准脑梗死二级预防及针对性肢体康复治疗基础上，结合杏芎氯化钠注射液治疗可以促使患者肢体功能从Fugle-MeyerⅠ、Ⅱ级向Ⅲ级好转。

Effect of floium ginkgo extract and tertram ethypyrazine sodium chloride injection on limb motor function in patients with cerebral infarction

ObjectiveTo observe and analyze the effect of Floium Ginkgo Extract and Tertram Ethypyrazine Sodium Chloride injection on limb motor function recovery in patients with cerebral infarction. MethodsTwo hundred patients with cerebral infarction hospitalized in the Department of Neurological Rehabilitation of the Fifth Affiliated Hospital of Guangzhou Medical University from February to October 2018 were randomly divided into two groups, 103 in the experimental group and 97 in the control group. The control group was given standard secondary prevention treatment and neurorehabilitation treatment for cerebral infarction, while the experimental group was treated with Floium Ginkgo Extract and Tertram Ethypyrazine Sodium Chloride injection on the basis of the control group. Brunnstrom stage and simplified Fugle-Meyer score were used to evaluate the motor function of the two groups before and after treatment. ResultsFrom the perspective of Brunnstrom staging, the motor function of hands, upper limbs and lower limbs in the experimental group was improved after 14 d of treatment compared with that before treatment, with statistical significance (P<0.05); the motor function of hands, upper limbs and lower limbs in the control group was improved after 14 d of treatment compared with that before treatment, with statistical significance (P<0.05). From the perspective of Fugle-Meyer score, 65 Fugle-Meyer grade Ⅰ and Ⅱ patients in the experimental group were assessed as grade Ⅲ after treatment, while 62 Fugle-Meyer grade Ⅰ and Ⅱ patients in the control group were assessed as grade Ⅲ after treatment, and 14 Fugle-Meyer grade Ⅲ patients were assessed as grade Ⅲ after treatment, the difference was statistically significant (P=0.046). The curative effect of the experimental group was higher than that of the control group. ConclusionThe treatment of experimental group and control group can improve the motor function of limbs in patients with cerebral infarction comprehensively and obviously. On the basis of standard secondary prevention of cerebral infarction and targeted limb rehabilitation treatment, combined with Floium Ginkgo Extract and Tertram Ethypyrazine Sodium Chloride injection can improve the limb function of patients from Fugle-Meyer Ⅰ and Ⅱ to Ⅲ.