| 血管紧张素转化酶、血管紧张素与认知 |
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| 引用本文： | 秦锦标. 血管紧张素转化酶、血管紧张素与认知[J]. 医学综述, 2009, 15(8): 1153-1155 |
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| 作者姓名： | 秦锦标 |
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| 作者单位： | 东南大学医学院附属南京江北人民医院神经内科,南京,210048 |
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| 摘 要： | 大量研究表明,肾素-血管紧张素系统中的血管紧张素转换酶、血管紧张素与认知关系密切:血管紧张素转化酶与认知的关系与其基因多态性有关,血管紧张素转化酶抑制剂能改善认知功能;血管紧张素Ⅱ可促进,也可抑制认知功能;血管紧张素Ⅳ对认知功能起促进作用;它们是通过不同的作用机制来影响认知功能的。本文简要阐述了血管紧张素转化酶、血管紧张素Ⅱ、血管紧张素Ⅳ与认知功能之间的关系,并初步探讨了影响的作用机制。
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| 关 键 词： | 血管紧张素转化酶 血管紧张素Ⅱ 血管紧张素Ⅳ 认知 |
Angiotensin-converting Enzyme,Angiotensin and Cognition |
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| QIN Jin-biao. Angiotensin-converting Enzyme,Angiotensin and Cognition[J]. Medical Recapitulate, 2009, 15(8): 1153-1155 |
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| Authors: | QIN Jin-biao |
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| Affiliation: | QIN Jin-biao. ( Department of Neurology, Nanjing Jiangbei People＇s Hospital,Nanjing 210048, China) |
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| Abstract: | A large number of studies have indicated that the association of angiotensin-converting enzyme,angiotensin and cognition is close. The association of angiotensin-converting enzyme and cognition is relative to the polymorphism. Angiotensin-converting enzyme inhibitors can improve cognition. Angiotensin Ⅱ can promote and inhibite cognition as well. Angiotensin Ⅳ can promote cognition. They affect cognition by different mechanism. This article briefly expounds the association of angiotensin-converting enzyme, angiotensin and cognition and the mechanism of effects. |
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| Keywords: | Angiotensin-converting enzyme Angiotensin Ⅱ Angiotensin Ⅳ Cognition |
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