宫颈环形电切术对妊娠结局的影响

目的探讨宫颈环形电切术（LEEP）对妊娠结局和分娩方式的影响。方法采用回顾性病例对照研究，选择因宫颈上皮内瘤变（CIN）1I～III而行宫颈环形电切术，于术后妊娠并分娩的31例产妇为研究组。按年龄、孕次、产次、经济收入相匹配的原则，选取同期分娩且孕前未行任何宫颈手术的产妇62例为对照组，2组均无并发症，观察2组间的早产儿发生率、胎膜早破发生率、分娩方式及新生儿体重等指标的差异。结果研究组早产率9．68％、胎膜早破发生率6．45％、剖宫产发生率41．94％、新生儿出生体重〈2500g者发生率6．45％；对照组早产率8．06％、胎膜早破发生率4．84％、剖宫产发生率38．71％、新生儿出生体重〈2500g者发生率4．84％，2组比较差异无统计学意义（P〉0．05）。结论LEEP可能对妊娠结局无不良影响。

The effect of loop electrical excision procedure on pregnancy outcome

Abstract ：Objective To investigate the effect of loop electrical excision procedure （LEEP） on the outcome of subsequent pregnancies and mode of deliveries. Methods A retrospective case-control study was performed. The study group enrolled 31 women,who gave birth after previous LEEP treatment CIN H -m. The control group had 62 women with no history of cervical surgery, who delivered within the same period and were matched by age, gestation, parity and income. Two groups had no complications. The information including preterm birth, premature rupture of membranes（ PROM ） , type of deliver- ies and birth weight of the two groups were collected. Results The incidence of preterm birth was 9.68% in study group and 8.06% in control group,the incidence of PROM was 6.45% in study group and 4.84% in control group,cesarean section rate was 41.94% in study group and 38.71% in control group. The incidence of low birth weight was 6.45% in study group and 4.84% in control group, there was no significant difference between the two groups（ P 〉 0.05 ）. Conclu- sion LEEP showed no bad effect on the outcome of subsequent pregnancies probably.