住院老年患者抑郁症的共病特征分析

目的探讨老年抑郁症患者共病其他精神障碍的情况和特点及相关因素。方法选择2007年8月-2012年8月共5年住院的老年抑郁症患者资料进行分析，共有100例患者，其中有共病的51例，无共病的49例。共病的丛小情况及丰}J关因索采川Pearson单因素及多元Logistic回归分析。结果①共病最多的是心境恶劣，依次怂酒精滥用及镇静催眠药物滥用。②Pearson因素分析提示共病的老年抑郁患者有更多的焦虑情绪及更多躯体痛状和植物神经系统症状。（3）Logistic回归分析提示抑郁心境（β=0．771，S．E．=0．572，Wald=52．391，OR：2．78，P〈0．05）、肌肉系统症状（β=0．636，S．E．=0．717，Wald=44．102，OR=2．23，P〈0．05）、植物神经系统（β=0．788，S．E．=0．545，Wald=39．092，OR=1．97，P〈0．05）以及会谈时行为表现（β=0．759，S．E．=0．505，Wald=27．112，OR=1．87，P〈0．05）为老年抑郁症共病的危险因素。结论老年抑郁症共病的特征是物质滥用比较明显，并且呈现更多的躯体症状和焦虑，为老年抑郁症的诊断和治疗增加难度。

Characteristics of medical comorbidity in hospitalized older men with late-life depression

Abstract：Objective To study the prevalence,characteristics and related factors of comorbidity in older men with late- life depression. Methods From August 2007 to August 2007, the clinical data of 100 patients with late-fife depression （51 cases with comorbidity, other 49 cases without comorbidity） were analyzed retrospectively. Pearson correlation and multiple logistic regression analysis were used to analyze the data. Results （1）most comorbidities were dysthymia, fol- lowed by alcohol abuse and sedative hypnotic drug abuse. （2）the elderly depression patients with eomorbidity were often with more anxiety, somatic symptoms and vegetative nervous system symptoms. （3）The depressive mood（β = 0. 771, S.E. =0. 771 , Wald = 52. 391, OR = 2.78, P 〈 0.05 ） , muscle system symptoms （β = 0. 636, S. E. = 0. 636, Wald = 44.102, OR = 2.23, P 〈 0.05 ） , plant nerve system （β = 0. 788, S. E. = 0. 788, Wald = 39. 092, OR = 1.97, P 〈 0.05 ） , and the behavior during talks（β = 0. 759,S. E. = 0. 759, Wald = 27.112, OR = 1.87,P 〈 0.05 ） were the risk factors of comorhidity of depression. Conclusion The characteristics of comorbidity in older men with late-life depression is the substance abuse, and render more body symptom and anxiety, this is not beneficial to the diagnosis and treatment of geriat- ric depression.