米索前列醇与催产素用于晚期妊娠低宫颈评分引产分娩方式的比较

目的:探讨小剂量米索前列醇阴道给药以及催产素对低宫颈评分患者的引产结局。方法:回顾性分析我院2012年3月至2013年2月产科低宫颈评分待产孕妇200例(米索前列醇组100例,A组;催产素组100例,B组)两组,比较两组剖宫产率、引产安全性、引产效果及新生儿情况。结果:两组年龄,孕周,产次及宫颈评分差异无统计学意义(P>0.05)。A组引产成功率明显高于B组(P<0.01)、剖宫产率低于B组(P<0.01)。两组头位难产、羊水污染率及新生儿Apgar评分差异无统计学意义(P>0.05)。结论:相对于催产素引产,对于低宫颈评分患者采用小剂量米索前列醇阴道给药引产方法安全有效,对控制剖宫产起到积极作用。

Cooperation of delivery modes between misoprostol and oxytocin induced labor in patients with low-Bishop-score pregnancy

Objective： To compare the induced efficacy of virginal Misoprostol administration （at a low dose） with oxytocin administration in low Bishop score patients. Methods： 200 hospitalized pregnant women with low-Bishopscores （from March 2012 to February 2013） were collected （100 patients in misoprostol group revived virginal Misoprostol administration and 100 patients in oxytocin group recived regular oxytocin administration） and retrospective analyzed. The success rate, Time from induction to delivery, First stage of labor, Second stage of la- bor, Postpartum hemorrhage in 2h, Cesarean section rate, Fetal distress, Stasis active rate, Contamination of amni- otic fluid and Apgar scores were compared between groups by using SPSS19.0. Results： Ages, pregnant weeks, pregnant times and Bishop-scores were similar than those in both groups （P〈0.05）. The success rate of induction of labor in group A was significantly higher than those in group B （P〈0. 001）, Cesarean section rate were signifi- cantly lower than that in group B （P〈0.01）. Stasis active rates, Contamination of amniotic fluid and Apgar scores were similar in both groups （P〈0.05）. Conclusion：Compared with oxytocin, vaginal misoprostol （at a low dose） induced labor is more likely effective and safe for cervical ripening and artificial labor, and no additional advantage is observed.