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急性冠状动脉综合征患者血清Hcy水平与冠状动脉病变的相关性
引用本文:王建军,高路,叶云,高红艳,田文华,靳瑞.急性冠状动脉综合征患者血清Hcy水平与冠状动脉病变的相关性[J].山西医科大学学报,2012,43(6):441-444.
作者姓名:王建军  高路  叶云  高红艳  田文华  靳瑞
作者单位:1. 西安医学院第一附属医院急诊科,西安,710077
2. 西安交通大学医学院第一附属医院急诊科
3. 西安医学院第一附属医院检验科
摘    要:目的探讨急性冠脉综合征(ACS)患者血清同型半胱氨酸(Hcy)水平与冠状动脉病变程度的关系及临床意义。方法 60例急性冠脉综合征患者作为研究组(包括急性心梗组30例、不稳定型心绞痛组30例),30例健康体检者作为对照组。所有人均取外周静脉血检测血清同型半胱氨酸(Hcy),分析血清同型半胱氨酸(Hcy)水平与Gensini评分的关系。结果与对照组比较,研究组Hcy明显增高,差异有统计学意义(P
关 键 词:急性冠脉综合征  同型半胱氨酸  Gensini评分

Correlation of homocystein with Gensini score in patients with acute coronary syndrome
WANG Jian-jun , GAO Lu , YE Yun , GAO Hong-yan , TIAN Wen-hua , JIN Rui.Correlation of homocystein with Gensini score in patients with acute coronary syndrome[J].Journal of Shanxi Medical University,2012,43(6):441-444.
Authors:WANG Jian-jun  GAO Lu  YE Yun  GAO Hong-yan  TIAN Wen-hua  JIN Rui
Institution:1(1Intensive Care Unit,First Affiliated Hospital of Xi’an Medical University,Xi’an 710077,China;2Intensive Care Unit,First Affiliated Hospital of Medical College of Xi’an Jiaotong University;3Dept of Laboratory Medicine,First Affiliated Hospital of Xi’an Medical University)
Abstract:Objective To investigate the correlation of homocystein(Hcy) in serum with Gensini score in patients with acute coronary syndrome(ACS).Methods Sixty patients with ACS were enrolled in this study,including 30 patients with acute myocardial infarction(AMI) and 30 patients with unstable angina pectoris(UAP).Thirty healthy subjects were chosen as control group.The lesions of coronary arteries were assessed.The relation of the serum level of Hcy with Gensini score was analyzed.Results The level of Hcy in serum was higher in patients with ACS than that in controls(P<0.05).Gensini score was significantly higher in AMI group than in UAP group(t=4.14,P<0.01).The level of Hcy was positively related with Gensini score in ACS patients(r=0.683,P<0.01).Conclusion Serum level of homocystein in patients with ACS is closely related to the atherosclerotic lesions of coronary arteries.
Keywords:acute coronary syndrome  homocystein  Gensini score
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